iiinova — where your digital self keeps evolving

Anne Vassalli @annevassalli.bsky.social · 22/06/2026

Excited to share our freshly published @nature.com Reviews Neurology Perspective ⭐️ 💎 #Narcolepsy may not just be the irreversible autoimmune killing of #hypocretin/orexin neurons but amenable to their functional restoration. rdcu.be/fpFes @fbm-unil.bsky.social #ali.seifinejad

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Anne Vassalli @annevassalli.bsky.social · 25/07/2025

Excited to share our new preprint! www.biorxiv.org/content/10.1... Divergent modulation of dopaminergic neurons by hypocretin/orexin receptors-1 and -2 shapes dopaminergic cell activity and socio-emotional behavior Tzanoulinou et al Supported by @snsf.ch

Summary depiction of divergent neuromodulation of dopaminergic neurons by hypocretin/orexin receptors-1 and -2 as reflected at electrophysiological and behavioral levels

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Reposted by Anne Vassalli

Habib Lab @shukryjhabib.bsky.social · 04/05/2025

Join us in Lausanne 🇨🇭 for the Lac Léman Regenerative Medicine Symposium, Sept 17–19, 2025! 🔬 Stem cells, aging, bioengineering — shaping the future of regenerative medicine. habiblab.org/l2rm 🎟️ Students 25 CHF | Postdocs/Faculty 50 CHF | Industry 150 CHF #L2RM #RegenMed #StemCells

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Anne Vassalli @annevassalli.bsky.social · 18/02/2025

Our follow-up study on the orexin↔dopamine neuronal interplay is here to share! We discover opposite action of #hypocretin/orexin A vs B via #OX1R vs #OX2R on VTADA cell excitability +demonstrate striking distinct impact of DA cell Ox1 vs 2R loss on mouse behavior in socioemotional&cognitive domain

biorxiv.org

Divergent modulation of dopaminergic neurons by hypocretin/orexin receptors-1 and -2 shapes dopaminergic cell activity and socio-emotional behavior

Many neuropsychiatric disorders involve dysregulation of the dopaminergic (DA) input to the forebrain. Of particular relevance are DA projections originating from the midbrain ventral tegmental area (...

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