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Annals of Allergy, Asthma & Immunology

@annalsacaai.bsky.social

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Annals of Allergy, Asthma & Immunology is a scholarly medical journal published monthly by the American College of Allergy, Asthma & Immunology. The publication is an objective evidence-based forum for the allergy/immunology specialist to keep up to date.

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Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 01/10/2026

Comparing COVID-19-associated with AERD-associated chemosensory dysfunction (CSD), a study compares qualitative and quantitative chemosensory alterations and quality-of-life impact. Which differences between the groups were most striking? www.annallergy.org/article/S108...

Unique and shared patterns of chemosensory dysfunction distinguish chronic COVID-19 and aspirin-exacerbated respiratory disease

Persistent chemosensory dysfunction (CSD) occurs in both COVID‑19 and aspirin-exacerbated respiratory disease (AERD). The similarities and differences in the chemosensory experiences of these 2 condit...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 29/09/2026

Is adding dupilumab to medium-dose inhaled corticosteroids (ICS) superior to continuing high-dose ICS in patients with uncontrolled, moderate-to-severe asthma? Read more: www.annallergy.org/article/S108...

Improved asthma outcomes with dupilumab plus medium-dose inhaled corticosteroids vs placebo plus high-dose inhaled corticosteroids

Escalating from medium-dose inhaled corticosteroid (ICS) to high-dose ICS in patients with asthma offers limited clinical benefit.

Reposted by Annals of Allergy, Asthma & Immunology

Pulmonology Advisor @pulmonologyadvisor.bsky.social · 26/09/2026

From @annalsacaai.bsky.social 🩺⬇️ Lower likelihood of #FoodAllergy resolution was associated with multiple factors, including lower income, limited health literacy, and #RacialDisparities.

pulmonologyadvisor.com

Socioeconomic Disparities Reduce Likelihood of Food Allergy Resolution in Children

Racial/ethnic disparities and worse socioeconomic conditions are associated with a reduced likelihood of FA resolution in children.

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 24/09/2026

This study assessed and evaluated the safety and efficacy of rapid drug desensitization for pediatric patients who had hypersensitivity reactions (HSRs) to chemotherapeutics, monoclonal antibodies, and disease-modifying antirheumatic drugs (DMARDs). Read more: www.annallergy.org/article/S108...

Rapid drug desensitization in pediatric patients

Drug hypersensitivity is often managed by drug desensitization, yet published data remain scarce in children. This study evaluated the safety and efficacy of rapid desensitization to chemotherapeutic ...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 22/09/2026

Building on the ORACLE studies, researchers examine the evidence supporting accessible type 2 (T2) inflammatory biomarkers—specifically blood eosinophils and fraction of exhaled nitric oxide (FeNO)—from initial diagnosis through treatment escalation. Learn more: www.annallergy.org/article/S108...

After the escalator

Asthma, the most common chronic respiratory disease, is characterized by variable symptoms, airflow limitation, and airway inflammation. Current management relies largely on a symptom-focused stepwise...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 17/09/2026

Distinguished Author Article: Precision medicine in AD strives to match defined phenotypes and molecular endotypes with the most appropriate therapy—from barrier-restoring topicals to systemic JAKis and biologics targeting IL-4, IL-13, or OX40 pathways. www.annallergy.org/article/S108...

Precision medicine in atopic dermatitis

Atopic dermatitis (AD) is a chronic, multifactorial inflammatory skin disease characterized by barrier dysfunction, immune dysregulation, genetic predisposition, and environmental factors, including m...

Reposted by Annals of Allergy, Asthma & Immunology

Pulmonology Advisor @pulmonologyadvisor.bsky.social · 16/09/2026

From @annalsacaai.bsky.social 🫁 Improvements in peripheral airway reactance via #BiologicTherapy were significantly associated with clinical remission in patients with severe #asthma, indicating small airways dysfunction as a potential treatable trait in this population. #PulmSky

pulmonologyadvisor.com

Clinical Remission in Asthma Linked to Improvements in Peripheral Airway Reactance

Patients with asthma who had improved peripheral airway reactance following biologics showed increased likelihood of clinical remission.

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 15/09/2026

Food allergy affects approximately 11% of adults and 8% of children in the United States. Individuals with food allergy and caregivers of children with food allergy support reforming precautionary allergen labeling through standardized, evidence-based approaches. www.annallergy.org/article/S108...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 10/09/2026

This article reviews implementation frameworks, including system-level approaches to embedding shared decision-making into routine care, and highlights equity-informed strategies to ensure that decisions are both values aligned and realistically achievable. www.annallergy.org/article/S108...

Communication, compassion, and shared decision-making in allergy

Shared decision-making (SDM) is a structured approach to clinical care that integrates the best available evidence, clinician expertise, and patient values. Although SDM frameworks are well described,...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 08/09/2026

The prevalence of eosinophilic esophagitis (EoE) has increased, and it is no longer considered a rare disease; it is also common in allergy-immunology patients. The role of the allergist in EoE is growing. Find out more: www.annallergy.org/article/S108...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 03/09/2026

Single maintenance and reliever therapy (SMART) is the guideline-recommended treatment for children with moderate to severe asthma, yet it is underutilized in pediatric practice. A new study aimed to find out why. www.annallergy.org/article/S108...

Clinician and family perspectives on the use of single maintenance and reliever therapy for children

Single maintenance and reliever therapy (SMART) is the guideline-recommended treatment for children with moderate to severe asthma, yet it is underutilized in pediatric practice.

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 01/09/2026

A double-blinded randomized crossover study evaluated the effects of a nasal budesonide spray on nasal cytokines, symptoms, patency, and epigenetics in patients with allergic rhinitis before and after repeated acute exposure to diesel exhaust. Find out more: www.annallergy.org/article/S108...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 27/08/2026

Do parents underestimate the emotional impact of food allergies on their older children? What is the psychosocial parental burden on families of children with food allergies? Learn more: www.annallergy.org/article/S108...

Predictors of psychosocial burden in parents of children with food allergy

The psychosocial burden of food allergy (FA) impacts the entire family, particularly the affected child and their parents.

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 25/08/2026

In Australia, the honeybee is a common cause for sting-related hospitalizations, accounting for up to 18% of anaphylaxis fatalities. A retrospective study adds real-world clinical experience of honeybee venom immunotherapy delivery in adult patients in Australia. www.annallergy.org/article/S108...

Honeybee venom immunotherapy: An Australian center experience of more than 15 years

Honeybee venom is a leading cause of anaphylaxis, and venom immunotherapy (VIT) reduces the risk of future severe reactions to stings.

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 20/08/2026

A 55-year-old male with no previous atopic history presented to the emergency department (ED) with several days of fever, severe abdominal pain, vomiting, and diarrhea. What could be causing this? Read this interesting case: www.annallergy.org/article/S108...

Hidden in plain sight

A 55-year-old male with no previous atopic history presented to the emergency department (ED) with several days of fever, severe abdominal pain, vomiting, and diarrhea. Although he had been having the...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 18/08/2026

A review synthesizes current knowledge on clinical phenotypes and molecular endotypes in EoE, highlighting how integrating these frameworks can improve risk stratification, inform treatment selection, and advance precision medicine. www.annallergy.org/article/S108...

Clinical heterogeneity and endotype stratification in eosinophilic esophagitis

Eosinophilic esophagitis (EoE) is a chronic immune-mediated inflammatory disease marked by esophageal dysfunction and eosinophilic inflammation, with significant variability in presentation, course, a...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 13/08/2026

Because EoE is a chronic disease that often requires serial reassessment during treatment initiation, food reintroduction, and long-term maintenance, dependence on repeated sedated endoscopies creates a major barrier to patient-centered care. Learn more: www.annallergy.org/article/S108...

Shifting the scope

Less invasive diagnostics that decrease dependence on sedated endoscopy are needed for eosinophilic esophagitis (EoE).

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 11/08/2026

A study has novel data on fish-induced FPIES in Greek children and highlights its distinctive epidemiologic & clinical characteristics. Although cow’s milk & soy are common triggers globally, fish has emerged as a significant culprit in the Mediterranean. www.annallergy.org/article/S108...

Natural history and clinical characteristics of fish-induced food protein-induced enterocolitis syndrome (FPIES) in Greek children

Food protein-induced enterocolitis syndrome (FPIES) is a non–IgE-mediated food allergy presenting in infancy with delayed gastrointestinal symptoms. Although cow’s milk and soy are common triggers glo...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 06/08/2026

How much influence do allergists have on family anxiety and worry about food allergies? Can discussions with an allergist reduce anxiety and worry? Do families feel comfortable discussing their worries with their allergist? Learn more: www.annallergy.org/article/S108...

Allergist impact on anxiety

Food allergy is a growing public health concern that can often lead to significant anxiety and worry for patients and their families.

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 04/08/2026

Asthma is a chronic respiratory disease in which up to 44% of patients require systemic corticosteroids annually. See the protocol for a study exploring whether dupilumab intervention can induce clinical remission in adults with at-risk type-2 inflammatory asthma. www.annallergy.org/article/S108...

Protocol for a multinational, investigator-initiated, parallel-group, randomized, double-blind, placebo-controlled phase 3b superiority trial assessing the effect of dupilumab on inducing clinical rem...

Asthma is a prevalent chronic respiratory disease in which up to 44% of patients require systemic corticosteroids annually. Many have active type-2 inflammation, characterized by elevated blood eosino...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 30/07/2026

Can vitamin D supplementation modulate neutrophilic inflammation in asthma? What are its effects in preschoolers with virus-induced asthma? Learn more in this article: www.annallergy.org/article/S108...

Impact of vitamin D status and supplementation on exploratory inflammatory biomarkers in preschoolers with asthma

Vitamin D supplementation may improve asthma by modulating inflammation, but its effects in preschoolers with virus-induced asthma remain underexplored.

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 28/07/2026

Can Mepolizumab treatment reduce acute and long-term corticosteroid effects in patients with severe asthma vs long-term systemic corticosteroid use? Read the latest: www.annallergy.org/article/S108...

Mepolizumab exhibits quantifiable reduction in corticosteroid-related adverse effects in severe asthma

Treatment that reduces systemic corticosteroid (SCS)–related adverse effects but maintains disease control is of broad public health importance.

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 22/07/2026

Emerging epidemiologic, genetic & mechanistic evidence supports that AD represents a systemic disease associated with a spectrum of immune-related comorbidities. Clinicians should maintain heightened vigilance for autoimmune symptoms in patients with AD. www.annallergy.org/article/S108...

Comorbidities of atopic dermatitis

Atopic dermatitis (AD) is the most common chronic inflammatory skin disease and has traditionally been viewed as a disorder confined to the skin. However, emerging epidemiologic, genetic, and mechanis...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 20/07/2026

Intranasal challenges have been the cornerstone of allergic rhinitis research, enabling controlled replication of natural allergen exposure and detailed characterization of nasal inflammatory responses. How does this apply to cat allergy? Find out: www.annallergy.org/article/S108...

Clinical symptoms and biomarkers of cat allergen–induced allergic rhinitis using the nasal allergen challenge model

The nasal allergen challenge (NAC) of the Allergic Rhinitis—Clinical Investigator Collaborative (AR-CIC) is a validated and reproducible model of allergic rhinitis (AR). To date, only seasonal allerge...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 16/07/2026

Which strategies can alleviate needle anxiety in pediatric allergy patients? This Master Clinician article presents evidence-based psychological strategies to reduce anxiety and help caregivers support their child during needle procedures. www.annallergy.org/article/S108...

Psychological strategies to reduce needle anxiety in pediatric allergy patients

As part of the master clinician series, we present our approach to the management of needle anxiety in pediatric patients. Our approach incorporates evidence-based coping strategies, pain management s...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 14/07/2026

The American College of Allergy, Asthma & Immunology (ACAAI) is supporting a trial initiative by Annals of Allergy, Asthma & Immunology to support Open Access of NIH-funded research. Learn more. www.annallergy.org/article/S108...

Open access is essential for research funded by the National Institutes of Health (NIH)

In July of 2025, the National Institutes of Health (NIH) instituted a new policy (the “2024 NIH Public Access Policy”) which requires that all publications from NIH-funded research be made publicly av...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 09/07/2026

Earn CME credit with Annals' CME online exams! Read an article in Annals, then take an exam for CME credit! Learn more: www.annallergy.org/cme/home

Annals of Allergy, Asthma & Immunology - CME

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 07/07/2026

Write an article for the highly cited Annals of Allergy, Asthma & Immunology! Here are our guidelines: www.annallergy.org/content/auth...

Information for Authors: Annals of Allergy, Asthma & Immunology

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 02/07/2026

In COVID-19 prevention and treatment, atopic disease was associated with heightened susceptibility to infection but better clinical outcomes. What improves clinical outcomes for both atopic and non-atopic individuals? www.annallergy.org/article/S108...

Effect of background asthma and atopic conditions on prophylaxis and treatment of COVID-19 infection

Electronic medical record database studies suggest that underlying allergic diathesis is a risk factor for COVID-19 but may attenuate outcomes.

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 30/06/2026

The Asthma Impairment and Risk Questionnaire is a validated, 10-item, low-literacy-demand, composite asthma control measure that assesses both current symptom-based impairment and exacerbation history-based risk for patients with asthma aged 12 years and older. www.annallergy.org/article/S108...

Asthma Impairment and Risk Questionnaire predicts short- and long-term exacerbation occurrence across asthma severities

The Asthma Impairment and Risk Questionnaire (AIRQ) predicts 12-month exacerbation occurrence for patients aged 12 years and older.

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 25/06/2026

IgE-mediated food allergy remains a major health concern affecting up to 10% of the population, with highest prevalence in children. This focused review highlights recent advances in biologic therapies, immunotherapy modalities, and dietary strategies. www.annallergy.org/article/S108...

7 for 11: Food allergy treatment therapies

IgE-mediated food allergy remains a major health concern affecting up to 10% of the population, with highest prevalence in children.1 This focused review highlights recent advances in biologic therapi...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 23/06/2026

Mild asthma has been associated with exacerbations, lung function decline, and even death. Importantly, mild asthma does not equate to no risk. To improve mild asthma care, a better understanding about providers’ beliefs and attitudes is needed. Learn more: www.annallergy.org/article/S108...

Treatment for mild asthma: What matters to providers

Most patients with asthma have mild asthma, but it has received less attention despite risks of exacerbation, lung function decline, and even death. Provider knowledge, practice patterns, and guidelin...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 18/06/2026

Do compromised ciliated cells and aberrant proliferation of basal cells drive eosinophilic inflammation in response to Type 2 inflammation in patients with allergic rhinitis combined with asthma? Learn more: www.annallergy.org/article/S108...

A single-cell atlas of the human airways from patients with allergic rhinitis comorbid with asthma

Single-cell RNA profiling has already been applied to normal airway samples, but no data set includes brushings collected from patients with allergic rhinitis combined with asthma (ARcoAS) at distinct...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 16/06/2026

In a cohort of 1,200 children on OIT at a tertiary pediatric hospital with robust OIT and EoE programs, the rate of newly diagnosed EoE during OIT was found to be 0.7%, which is lower than prior studies. Learn more: www.annallergy.org/article/S108...

Eosinophilic esophagitis incidence during single and multiple food oral immunotherapy

In the past decade, significant progress has occurred with using oral immunotherapy (OIT) in the treatment of IgE–mediated food allergies. Eosinophilic esophagitis (EoE) is a known potential adverse e...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 11/06/2026

This study was a prospective, longitudinal cohort embedded within the Hong Kong Drug Allergy Delabelling Initiative. Adults referred for suspected penicillin allergy underwent standardized evaluation including skin test and drug provocation test. Learn more. www.annallergy.org/article/S108...

Prospective outcomes of penicillin allergy evaluation

Inaccurate penicillin allergy (PA) labels are associated with clinical and public health burdens. Although delabeling programs are effective, long-term data on the sustainability of delabeling and pat...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 09/06/2026

There have been significant breakthroughs in understanding the pathophysiology of hereditary angioedema in the past several years. This Yardstick provides evidence-based, expert opinion on how to diagnose and manage pediatric and adolescent hereditary angioedema. www.annallergy.org/article/S108...

Diagnosis and management of pediatric and adolescent hereditary angioedema

There have been significant breakthroughs in understanding the pathophysiology of hereditary angioedema in the past several years. Owing to this, patients now have several therapeutic options for mana...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 04/06/2026

Venom immunotherapy remains the only disease-modifying treatment for Hymenoptera (stinging insect) venom allergy. This study evaluates safety and efficacy of a novel 4-day outpatient VIT buildup protocol compared with established inpatient rush and ultrarush regimens. bit.ly/4uCR7xW

Novel 4-day outpatient Hymenoptera venom immunotherapy buildup protocol with low reaction rates

Hymenoptera stings can cause severe systemic reactions, including life-threatening anaphylaxis. Venom immunotherapy (VIT) remains the only disease-modifying treatment for Hymenoptera venom allergy. Co...

Reposted by Annals of Allergy, Asthma & Immunology

Annals of Allergy, Asthma, & Immunology Editor-in-Chief @annalseditor.bsky.social · 02/06/2026

The June issue of Annals of Allergy, Asthma & Immunology explores #remission in #food #allergy. The exciting "7 for 11 series" reviews #foodallergy and #anaphylaxis. Helping you provide the best care to your patients! @annalsacaai.bsky.social #Medsky www.annallergy.org/current

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 02/06/2026

This review considers how biologic therapies have improved outcomes in severe asthma, and what research is needed to improve clinical remission rates. How can patient selection help target the underlying biological process in order to optimize the impact of biologic therapy? bit.ly/48Uj5Nt

Lessons learned regarding optimal use of biologics to achieve disease remission in severe asthma

Severe asthma management has changed dramatically in the last decade after the introduction of T2-directed biologic therapies. This has enabled more ambitious treatment goals, including on-treatment c...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 28/05/2026

Annals of Allergy, Asthma & Immunology’s commitment to aiding clinical allergists in their care of patients is well reflected in this month’s edition, which is dedicated to the treatment of asthma. Find out what's new in the care of patients with asthma. bit.ly/42xyMXf

What’s new in the care of patients with asthma?

Annals of Allergy, Asthma & Immunology’s commitment to aiding clinical allergists in their care of patients is well reflected in this month’s edition, which is dedicated to the treatment of asthma.

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 26/05/2026

Is there cross-reactivity between amoxycillin and piperacillin-tazobactam? If so, how can an allergist best protect those at risk? Learn how this study aims to establish a link between the two and what the results show for safer patient care. bit.ly/490rvD3

Cross-reactivity between amoxicillin and piperacillin–tazobactam in patients with amoxicillin allergy: A prospective study

Amoxicillin (AX) is the most frequently prescribed β-lactam antibiotic in the USA and Europe and a leading cause of drug-induced hypersensitivity. Although cross-reactivity between aminopenicillins an...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 21/05/2026

Longitudinal changes in percentage of forced expiratory volume in 1 second allows clustering of patients with severe asthma into 3 groups with disparate clinical and inflammatory profiles, which may drive treatment choice. bit.ly/4u8oyZs

Clustering of patients with severe asthma based on long-term percentage of forced expiratory volume in 1 second (FEV1) changes

Severe asthma is a heterogeneous disease with variable clinical manifestations and treatment responses. Long-term assessment of lung function trajectories may help define phenotypic and endotypic subg...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 20/05/2026

The American College of Allergy, Asthma & Immunology (ACAAI) is supporting a trial initiative by Annals of Allergy, Asthma & Immunology to support Open Access of NIH-funded research. Learn more. www.annallergy.org/article/S108...

Open access is essential for research funded by the National Institutes of Health (NIH)

In July of 2025, the National Institutes of Health (NIH) instituted a new policy (the “2024 NIH Public Access Policy”) which requires that all publications from NIH-funded research be made publicly av...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 19/05/2026

50-91% of asthma patients of all disease severities have small airways dysfunction. This study compares the aerodynamic particle size distribution of 3 triple combination inhalers to discern which best targets the small airways. bit.ly/42xDWm4

Relative particle size and distribution of inhaled triple therapies

Many patients with asthma or chronic obstructive pulmonary disease have small airways dysfunction, the presence of which has clinical implications including poor disease control and worse health statu...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 15/05/2026

Improving asthma control in pregnancy requires consistent, evidence-based messaging, multidisciplinary care, and shared decision-making. This CME review focuses on strategies to optimize asthma control throughout pregnancy. Learn more: bit.ly/4376H9m

Asthma in pregnancy: Optimizing treatment strategies and the emerging role of biologic therapies

Asthma is the most common chronic respiratory disease during pregnancy and is a major contributor to preventable maternal morbidity and adverse fetal outcomes when poorly controlled. Although most ast...

Reposted by Annals of Allergy, Asthma & Immunology

Annals of Allergy, Asthma, & Immunology Editor-in-Chief @annalseditor.bsky.social · 08/05/2026

The May issue of Annals of #Allergy, Asthma & #Immunology has bloomed! This month is all about #asthma -- read up to find out the latest information so you can provide the best care to your patients! #medsky @annalsacaai.bsky.social www.annallergy.org/current

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 13/05/2026

Does the lack of detectable IgE predict noninfectious complications of common variable immunodeficiency (CVID)? Find out in this study of 149 patients with CVID. bit.ly/433jIAP

Undetectable IgE association with noninfectious complications of common variable immune deficiency

Undetectable IgE levels are a frequent feature of common variable immunodeficiency (CVID). However, not much is known regarding the role of IgE levels as a prognostic factor in patients with CVID.

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 07/05/2026

This Distinguished Author review outlines the early history of common variable immunodeficiency (CVID), diagnostic criteria and workup of subjects, clinical manifestations, emerging genetic understandings, and current treatment for patients with this immune defect. www.annallergy.org/article/S108...

Current concepts: Common variable immunodeficiency

Common variable immunodeficiency (CVID) is the most frequent symptomatic primary immunodeficiency disorder found in clinical medicine. The immune defect occurs in males and females equally and is char...

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 05/05/2026

Dupilumab significantly and rapidly improved asthma symptoms, pulmonary function, and FeNO values in patients with asthma comorbid with refractory eosinophilic chronic rhinosinusitis, and these improvements were sustained over time. Find out more: www.annallergy.org/article/S108...

Clinical remission of comorbid asthma during dupilumab treatment in patients with high-burden eosinophilic chronic rhinosinusitis

Eosinophilic chronic rhinosinusitis (ECRS), a refractory subtype of chronic rhinosinusitis, frequently coexists with asthma. CRS can exacerbate the asthma burden, contributing to poor disease control....

Annals of Allergy, Asthma & Immunology @annalsacaai.bsky.social · 30/04/2026

The pharmacokinetics and pharmacodynamics of single dose and repeat doses of sublingual (AQST-109) and intramuscular epinephrine were compared in healthy adults. Learn how they compared: www.annallergy.org/article/S108...

Pharmacokinetics and pharmacodynamics of AQST-109

Intramuscular epinephrine administered via manual injection, autoinjector, or as a nasal spray are the current first-line treatments for anaphylaxis. AQST-109 is a needle- and device-free sublingual a...