Underrepresentation of disabled groups in clinical trials results in an inadequate evidence base for their clinical care, which drives health inequalities. This study aims to review and map the potential barriers and facilitators to the recruitment ...

In clinical trials, post-randomisation events, such as treatment discontinuation or the use of rescue medication, can complicate the interpretation of results. An estimand is a precise description of ...

Background Lower rates of participation in research by ethnic minority groups and socioeconomically deprived populations has led to efforts to develop recruitment strategies which aim to address this ...

The Pragmatic-Explanatory Continuum Indicator Summary (PRECIS-2) tool has been widely used to help investigators design randomised trials, facilitating the task of aligning design choices with an expl...

A new campaign at UCC aims to make health research more inclusive, to include under-served groups...

Estimating the risk of long COVID is challenging because many of its symptoms are associated with other conditions. Here, the authors conduct a systematic review and meta-analysis of studies that esti...

The pragmatic-explanatory continuum indicator summary (PRECIS) tools were created to help researchers design better studies. The tools were developed mainly by researchers from developed Western natio...

Healthcare accounts for 4% of the overall greenhouse gas emissions worldwide. Reducing carbon emissions is a key strategic aim for health systems in multiple countries. To achieve this, environmental ...

Patients can locate trials for potential enrolment in their area

We have undertaken a series of 10 evidence reviews for NHS England and here highlight seven interventions and programmes with the strongest evidence base.

The pragmatic explanatory continuum indicator summary (PRECIS) tool, initially published in 2009 and revised in 2015, was created to assist trialists …