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Andrew Hires

@andrewhires.bsky.social
884 followers 235 following 109 posts

Job: Neurobiology @ USC Likes: Bikes, crypto, techno What’s next?

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Andrew Hires @andrewhires.bsky.social · 07/04/2026
Most important piece I've read on AI this year. x.com/WillManidis/...
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Andrew Hires @andrewhires.bsky.social · 07/01/2026
Palisades Fire Exactly one year ago, on this spot, a fire broke out that destroyed our city. The surrounds and community look very different today. These massive disasters will continue until these specific factors are addressed and mitigated. Reasons for the disaster below (a partial list):
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Andrew Hires @andrewhires.bsky.social · 10/05/2025
What’s the next number in this sequence (just handed to me by my 6yo son). Simple but stumped me and GPT.
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Andrew Hires @andrewhires.bsky.social · 08/05/2025
Today, I gave an informal seminar to students and faculty on the accelerating impact new AI models like o3 will have on research and how to navigate those changes. Check it out👇 Resistance is Futile: AGI-Augmented Research and the New Scientific Method youtu.be/x6gv68fHw7Q?... via @YouTube
youtu.be
Resistance is Futile: AGI-Augmented Research and the New Scientific Method
YouTube video by Samuel Hires
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Andrew Hires @andrewhires.bsky.social · 07/05/2025
Best view at USC.
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Andrew Hires @andrewhires.bsky.social · 06/05/2025
It's been 3.5 months since this experiment on scientific reasoning. The improvements in SOTA models since are remarkable. Here's OpenAI's o3 model's first attempt at reviewing my 2017 R01-A1 submission. Would you do a better job?
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Andrew Hires @andrewhires.bsky.social · 30/04/2025
If you don't realize that AGI is already here, you must be too lazy or incurious to try o3.
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Andrew Hires @andrewhires.bsky.social · 26/01/2025
Testing out DeepSeek-R1's ability to do "science" in one-shot. I asked it to critique my 2017 R01 proposal (Impact 26, 10%, funded by NINDS. I wrote the proposal, have rights to share it. It's first-shot response is indistinguishable from a median quality reviewer's. What do we do now?
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Andrew Hires @andrewhires.bsky.social · 08/01/2025
If anyone wants to follow along, I have a bunch of media posts on X. Sorry no time to duplicate. Pacific Palisades is mostly destroyed. Half my friends have lost their homes. Mine not gone yet but not looking good.
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Andrew Hires @andrewhires.bsky.social · 07/01/2025
How my day is going #PalisadesFire
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Andrew Hires @andrewhires.bsky.social · 01/01/2025
Good morning 2025! Thank you LAFD!
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Andrew Hires @andrewhires.bsky.social · 28/11/2024
Bringing my cooking talents to Bluesky
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Andrew Hires @andrewhires.bsky.social · 26/11/2024
New surf break
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Andrew Hires @andrewhires.bsky.social · 25/11/2024
I’ll tend to keep crypto posts off here, but there is an intriguing niche of the space that’s exploded in last 4 weeks. Jailbroken AI agents are augmenting training, tweeting bangers, and even dropping 🔥 mixtapes, all funded by their own memecoins people are bidding. Leaders are Zerebro and Goat.
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Reposted by Andrew Hires
David A. Markowitz @davidamarkowitz.bsky.social · 12/11/2024
One cultural rift I've observed in neuroscience: Connectomics folks tend to be firm in their belief that only a dense connectome is useful, sparse reconstructions need not apply. Meanwhile physiologists are content to randomly sample a few neurons here and there...
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Andrew Hires @andrewhires.bsky.social · 24/11/2024
Proof of life and hood tour with the USC prof crew, Mahdi and Lars.
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Andrew Hires @andrewhires.bsky.social · 22/11/2024
Hi all, This below account with two ‘s’ is an imposter, please report and don’t interact with DMs from it. Stay safe! 🙏 bsky.app/profile/andr...
bsky.app
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Andrew Hires @andrewhires.bsky.social · 14/11/2024
This paper is incredible. EM level connectomics on a light microscope. www.biorxiv.org/content/10.1...
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Andrew Hires @andrewhires.bsky.social · 12/11/2024
Who’s heading to Austin for CZI? 🙋‍♂️
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Andrew Hires @andrewhires.bsky.social · 26/12/2023
Blast from the past: The Investigator : UCSD Neuromovie 2005 youtu.be/-Yf7wA6TAHY?... Could use an editor tbh…
youtu.be
https://www.youtube.com/watch?si=acBXPJ0RSNkinLDb&v=-Yf7wA6TAHY&feature=youtu.be
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Reposted by Andrew Hires
Trisha Elliott @trishaelliott.bsky.social · 24/10/2023
There are rules! I only found this out quite recently! “The rule is that multiple adjectives are always ranked accordingly: opinion, size, age, shape, colour, origin, material, purpose.” www.theguardian.com/commentisfre...
theguardian.com
Order force: the old grammar rule we all obey without realising | Tim Dowling
I had no idea there was a specific order for adjectives until I read a viral post. It was a side-of-the-mallet moment
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Andrew Hires @andrewhires.bsky.social · 24/10/2023
Good morning
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Andrew Hires @andrewhires.bsky.social · 18/10/2023
New desert house mix from the USC Neuroscience Graduate Program retreat last weekend. www.mixcloud.com/sahires/usc-...
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Andrew Hires @andrewhires.bsky.social · 07/10/2023
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Andrew Hires @andrewhires.bsky.social · 04/10/2023
Quick math test: 230 - 220 x 0.5 = ? You probably won't believe it, but the answer is 5!
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Andrew Hires @andrewhires.bsky.social · 01/10/2023
Not bad. Reducing bike course by 45% certainly hurt placing. Fastest AG bike split. Better than expected run. If I can fix my horrible ocean swim and take transitions seriously, maybe can podium in the 45-49 AG next year.
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Andrew Hires @andrewhires.bsky.social · 01/10/2023
LFG
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Andrew Hires @andrewhires.bsky.social · 30/09/2023
Anyone in dance music in Boston 1995-05 felt Shalako’s influence. Satellite Records, Redlight raves, techno and jungle weeklies at the Phoenix Landing. All his work. His sunset set from our summer party is playing 9pm PDT tonight on 99.1 in LA & online www.klbp.org
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Andrew Hires @andrewhires.bsky.social · 29/09/2023
Results of the #legmullet experiment. TLDR: full shave with ankle socks beats all variations. strava.app.link/5nOsXgoutDb
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Andrew Hires @andrewhires.bsky.social · 28/09/2023
Preparing a landmark study of practical aerodynamics. Results tomorrow.
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Andrew Hires @andrewhires.bsky.social · 26/09/2023
Cannot believe we approved molnupiravir, when it was obvious it would increase SARS-Cov-2 genetic diversity and potentially transmission fitness when considered at a global population level. Corrupt policymaking. www.nature.com/articles/s41...
nature.com
A molnupiravir-associated mutational signature in global SARS-CoV-2 genomes - Nature
Nature - A molnupiravir-associated mutational signature in global SARS-CoV-2 genomes
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Andrew Hires @andrewhires.bsky.social · 24/09/2023
Tire swap from gravel Pathfinder Pro 32s to aero and rolling resistance optimized Continental GP5000 S TR 30s complete. Ready to race, if the race is ready.
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Andrew Hires @andrewhires.bsky.social · 24/09/2023
Max giving me some math questions. He invented two math symbols. Guess what they mean.
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Andrew Hires @andrewhires.bsky.social · 24/09/2023
Trust, but verify. Show my your Strava.
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Andrew Hires @andrewhires.bsky.social · 23/09/2023
Wow. Computer graphics have really progressed since Nethack 3.6.7 was released in February.
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Andrew Hires @andrewhires.bsky.social · 23/09/2023
It’s nearly the one year anniversary of the QQL generative art project by Tyler Hobbes and Dandelion Wist You can generate infinite art via algorithm at qql.art but to add to the official collection requires a mint pass. Very cool. Check the vibe in this video. vimeo.com/867362731
qql.art
QQL
An experiment in collaborative generative art, by Tyler Hobbs and Dandelion Wist
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Andrew Hires @andrewhires.bsky.social · 23/09/2023
Explaining bits and bytes to Maxwell. Growing up with a 2400 baud modem, I’m amazed we invented systems that can stream 360,000,000 bits of information per second from a distant machine to mine via invisible electromagnetic radiation. And do it in parallel to millions of machines in the world.
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Andrew Hires @andrewhires.bsky.social · 20/09/2023
Malibu Triathlon, one of the best in the country, might be cancelled because last winters rain flooded a PCH underpass by Zuma beach and a fish experiencing homelessness has taken up residence in the underpass.
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Andrew Hires @andrewhires.bsky.social · 17/09/2023
Mulholland Ride. Full Mulholland Drive and Highway loop with Mark Chaisson. Amazed William Mulholland built this, Barbara Fine preserved the middle as a dirt road, and thankful we can ride this epic 55-mile road across the Santa Monica mountains. strava.app.link/vUkP2cn2aDb
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Andrew Hires @andrewhires.bsky.social · 16/09/2023
Do not drill the glass.
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Andrew Hires @andrewhires.bsky.social · 15/09/2023
Which square is the least likely for a king to be on in chess? -Max, age 5 Anyone run the numbers on this before?
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Andrew Hires @andrewhires.bsky.social · 14/09/2023
This is the geographic center of Los Angeles.
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Andrew Hires @andrewhires.bsky.social · 14/09/2023
Obsessed with this idea…
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Andrew Hires @andrewhires.bsky.social · 13/09/2023
After squandering my early bsky presence due to inability to wean myself from 14 years of pseudo-clout inertia, I've ported my following list. Fuck it we ball.
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Andrew Hires @andrewhires.bsky.social · 13/09/2023
The PE stands for Placebo Effect. www.dailymail.co.uk/health/artic...
dailymail.co.uk
FDA to rule on pulling Benadryl and Sudafed from pharmacy shelves
The Food and Drug Administration ruled that a common medicine for nasal stuffiness found in common decongestants is ineffective. It is metabolized in the gut and doesn't reach the nose.
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Andrew Hires @andrewhires.bsky.social · 11/09/2023
Current status: Live-streaming 200ft lava fountains. www.youtube.com/live/tBh-ZhI...
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Andrew Hires @andrewhires.bsky.social · 31/08/2023
Real time cracking of RSA 2048 encryption via GPU accelerated complex number differential equations. Big if true! www.memcpu.com/tem_08_31_23/
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Andrew Hires @andrewhires.bsky.social · 02/06/2023
Namaste 🙏
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Andrew Hires @andrewhires.bsky.social · 14/05/2023
The baker invented CDOs.
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Andrew Hires @andrewhires.bsky.social · 13/05/2023
Going up
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