iiinova — where your digital self keeps evolving

Andre Rendeiro @andre-rendeiro.com · 15/09/2026

🚨 New preprint from the Rendeiro lab! We mapped human tissue aging at single-cell resolution: 3.5 billion cells, 16 organs, 980 donors, spanning the adult lifespan. Led by @e-abila.bsky.social 📄 www.biorxiv.org/content/10.6...

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Andre Rendeiro @andre-rendeiro.com · 07/08/2026

Excited to share StainX: GPU-accelerated batch stain normalization for histopathology images, with major speedups over standard PyTorch. Led by Samir Moustafa in our lab. 📄 doi.org/10.64898/202... 💻 github.com/rendeirolab/... #ComputationalPathology #DigitalPathology

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Andre Rendeiro @andre-rendeiro.com · 19/07/2026

Congratulations to Ariadna Villanueva Marijuan on receiving the DOC Fellowship from the Austrian Academy of Sciences (ÖAW)! I am proud of your hard work and dedication, Ariadna. Congratulations on the well-deserved achievement!

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Andre Rendeiro @andre-rendeiro.com · 20/03/2026

🎉 LazySlide published in Nature Methods! Open-source framework bridging computational pathology with the scverse ecosystem. Thanks to @yimin-zheng.bsky.social for leading this, the Rendeiro Lab, and the amazing community support! 📄 www.nature.com/articles/s41... 📝 rendeiro.group/p/lazyslide-...

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Andre Rendeiro @andre-rendeiro.com · 15/10/2025

Aging reshapes local tissue interactions but most organs retain a resilient overall architecture. Our atlas provides a new framework to study tissue structure, resilience, and aging. 🔬 Learn more: rendeiro.group

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Andre Rendeiro @andre-rendeiro.com · 15/10/2025

Among 100+ biological and clinical factors, age was the main driver of microanatomical changes. About 27% of domains shift in abundance over adulthood, yet others remain remarkably stable.

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Andre Rendeiro @andre-rendeiro.com · 15/10/2025

We developed H&E-UTAG, an unsupervised method that detects recurrent microanatomical domains directly from H&E slides. It identified 218 domains across 40 tissues and 29 organs — revealing how cellular organization underlies organ function.

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Andre Rendeiro @andre-rendeiro.com · 15/10/2025

New work from Iva Buljan @ivabuljan.bsky.social in our lab! We mapped how human tissue architecture changes with age using ~25k histology slides from 983 donors. This is the first body-wide atlas of human microanatomy. 📄 Preprint: www.biorxiv.org/content/10.1...

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Andre Rendeiro @andre-rendeiro.com · 26/09/2025

Great to be at the 2025 @OeGMBT meeting in Innsbruck and hear the diverse research made by the local community, in particular by the young researchers who presented their work. Thank you to the organizers, and to Markus Mandl for the invitation to talk!

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Andre Rendeiro @andre-rendeiro.com · 12/09/2025

Congratulations to Lisa Kleissl in our group, who won the best short talk award at the FEBS Advanced Course on Immunology, metabolism and ageing in Matrei am Brenner, Austria!

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Andre Rendeiro @andre-rendeiro.com · 03/09/2025

Our group is in Gumpoldskirchen, Austria, for our first lab retreat! It is a fantastic opportunity to get together and discuss our research projects, share ideas, and engage in some team building. A big thank you to everyone in the team, who together make it a privilege and honor to do this job.

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Andre Rendeiro @andre-rendeiro.com · 16/07/2025

LazySlide 🦥 just hit 100 GitHub stars! 🎉 Our free, open-source framework is making whole slide analysis easier than ever. Built on scverse 🐍, it handles everything from tissue segmentation to multi-omics workflows 🤹 & deep learning 🏋️. Big thanks to the community! www.biorxiv.org/content/10.1...

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Andre Rendeiro @andre-rendeiro.com · 01/06/2025

🔬 Whole slide histopathology images are a goldmine for tissue biology and diagnostics - but too often locked away in inaccessible formats or tools. In our new preprint, we introduce LazySlide: an open-source, modular, and interoperable framework. www.biorxiv.org/content/10.1...

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Andre Rendeiro @andre-rendeiro.com · 17/01/2025

🚨 Only a few days left to apply! 🚨 Join our interdisciplinary lab through the CeMM PhD Program! We're hiring PhD students in computational and systems biology. 📄 Learn more & apply: apply.cemm.at

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Andre Rendeiro @andre-rendeiro.com · 07/01/2025

Yimin's paper on a a novel visualization paradigm and implementation of cross-layout visualizations is now published in the journal Genome Biology (genomebiology.biomedcentral.com/articles/10....). Check it out at github.com/Marsilea-viz...

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Andre Rendeiro @andre-rendeiro.com · 16/12/2024

Thank you to our friends @gmivienna.bsky.social for the very nice and on point Arabidopsis histology-inspired season greetings, happy holidays!

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Andre Rendeiro @andre-rendeiro.com · 16/12/2024

Proud of Iva Buljan, PhD student in the lab, who gave a talk and presented a poster at the inaugural meeting of the European Society for Spatial Biology in Berlin, Germany last week!

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Andre Rendeiro @andre-rendeiro.com · 03/12/2024

Ejner Molten @ Austrian personalized medicine conference: data [harmonization, sharing, annotation, ...] is the largest barrier to personalized medicine implementation in Europe

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Andre Rendeiro @andre-rendeiro.com · 28/11/2024

Our lab had a lot of fun last night doing an escape room adventure and trying out new food at a Spanish tapas restaurant. More news at: rendeiro.group/news/

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Andre Rendeiro @andre-rendeiro.com · 16/11/2024

As rich as these insights are, many tissues are not accessible in the real world. We combined the image-based age predictions with blood gene expression data, resulting in new blood biological age predictors that are tissue-specific! These were higher in individuals with disease

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Andre Rendeiro @andre-rendeiro.com · 16/11/2024

But not all tissues, organs or individuals age in the same way. Tissue-specific clocks allowed us to identify waves of accelerated aging, classify individuals by their most aged organs, and demographic, lifestyle and clinical associations with specific acceleration of organs.

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Andre Rendeiro @andre-rendeiro.com · 16/11/2024

From these deep tissue features, we build biological age clocks with mean prediction error of 4.9 years, which are associated with telomere length, subclinical pathologies, and comorbidities. Tissue structure tell us more about biological age than chronological age!

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Andre Rendeiro @andre-rendeiro.com · 16/11/2024

We fine-tune #deeplearning models on healthy human tissue images, which enables us to augment them with super rich features highlighting and quantifying various aspects of tissue biology across scales in a systematic manner.

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Andre Rendeiro @andre-rendeiro.com · 16/11/2024

The GTEx project, with over 25,000 images of healthy tissue from almost 1000 individuals provides a phenomenal resource to address these questions www.nature.com/articles/ng....

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Andre Rendeiro @andre-rendeiro.com · 16/11/2024

For many human tissues it is not known how molecular and cellular aging changes lead to the decline of physiological function. This work is a step towards the systematic quantification of the aging process in human tissues at scale.

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Andre Rendeiro @andre-rendeiro.com · 16/11/2024

What if we could look at a human tissue image🔬and quantify its biological age?🧬 And how could we get the same insights without collecting the tissue sample? In our new @biorxivpreprint, we create "tissue clocks" ⏳to do just that! www.biorxiv.org/content/10.1... 📝 #aging #tissue thread below⬇️

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Andre Rendeiro @andre-rendeiro.com · 15/11/2024

The new Center for Translational Medicine of the Medical University of Vienna boasts a very impressive building facade: Klimt's Medicine - congratulations on the bold choice and importance of restoring this artwork to a place of significance 👏

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Andre Rendeiro @andre-rendeiro.com · 13/11/2024

Ernesto Abila presenting his poster on profiling cell aging cells in histopathological images at the Frontiers in Single Cell Genomics meeting organized by Cold Spring Harbor Asia in Japan🧬🔬

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Andre Rendeiro @andre-rendeiro.com · 09/10/2024

Excited with our new NVIDIA H100 GPUs now up and running in our HGX nodes at CeMM! Thanks a lot to the IT team! This will supercharge our computational power and accelerate breakthroughs in human health and aging research🧬

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Andre Rendeiro @andre-rendeiro.com · 19/02/2024

Want to visualize complex data without compromising on inter-feature relationships? Try Marsilea: a framework implementing a novel conceptual approach led by Yimin Zheng, now a postdoc in my group at CeMM www.biorxiv.org/content/10.1... marsilea.readthedocs.io/en/latest/

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