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Analytical Methods

@analyticalmethods.rsc.org
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The home of discoveries in the applied analytical and bioanalytical sciences, for the benefit of society and humanity. Published by @rsc.org 🌐 Website: rsc.li/analyticalmethods

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Analytical Methods @analyticalmethods.rsc.org · 28/09/2026
Repeatability and reproducibility of chromatographic parameters and resulting figures of merit on polyester C-CP fiber columns for the routine isolation and analysis of HEK293-derived extracellular vesicles. #OpenAccess from Raphael Ewonde Ewonde & R. Kenneth Marcus pubs.rsc.org/ay/article/d...
front cover of issue 36 of Analytical Methods
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Analytical Methods @analyticalmethods.rsc.org · 21/09/2026
On the front cover of issue 35 of Analytical Methods: Recent advances in carbon material-based electrochemical sensors for the detection of pesticide residues. ZhiLiang Wu, GuoCong Liu et al. pubs.rsc.org/ay/article/d...
front cover of issue 35 of Analytical Methods
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Analytical Methods @analyticalmethods.rsc.org · 14/09/2026
On the front cover of issue 34 of Analytical Methods: Effect of pH variation on Raman-based quantification of active pharmaceutical ingredients: implications for model accuracy and robustness. Yusui Sato. pubs.rsc.org/ay/article/d...
front cover of issue 34 of Analytical Methods
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Analytical Methods @analyticalmethods.rsc.org · 03/09/2026
On the front cover of issue 33 of Analytical Methods: Single particle – MC-ICP-MS for isotopic analysis of uranium particles. #OpenAccess from Benjamin T. Manard, Hunter B. Andrews et al. Read now: pubs.rsc.org/ay/article/d...
front cover of issue 33 of Analytical Methods
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Analytical Methods @analyticalmethods.rsc.org · 24/08/2026
Eco-friendly flow injection amperometric determination of tert-butylhydroquinone in edible oil samples using micelle-mediated reverse-phase dispersive liquid–liquid microextraction and an unmodified screen-printed carbon electrode. César Ricardo Teixeira Tarley et al. pubs.rsc.org/ay/article/d...
On the front cover of issue 32. Central micelle next to analytical instrument
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Analytical Methods @analyticalmethods.rsc.org · 18/08/2026
On the front cover of issue 31 of Analytical Methods: 3D-printed electrochemical sensors for sustainable electroanalysis: a critical assessment of materials, green strategies, and circular economy perspectives. Diego Rocha et al. pubs.rsc.org/ay/article/d...
front cover of issue 31 of Analytical Methods
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Analytical Methods @analyticalmethods.rsc.org · 03/08/2026
On the front cover of issue 29 of Analytical Methods: Revisiting biofilm quantification: crystal violet assay and the emerging role of hyperspectral imaging. #OpenAccess from Jayaseelan Murugaiyan et al. Read now: pubs.rsc.org/ay/article/d...
front cover of issue 29 of Analytical Methods
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Analytical Methods @analyticalmethods.rsc.org · 27/07/2026
On the front cover of issue 28 of Analytical Methods: Real-time detection of microbial aerobic plate count in salmon fillets based on near-infrared-hyperspectral imaging. Tao Pan, Lijun Yao et al. pubs.rsc.org/ay/article/d...
front cover of issue 28 of Analytical Methods: Near-infrared hyperspectral imaging for real-time detection of microbial aerobic plate count in salmon fillets.
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Analytical Methods @analyticalmethods.rsc.org · 20/07/2026
On the front cover of issue 27 of Analytical Methods: Development of a paper-based analytical device for the detection of polycyclic aromatic hydrocarbons (PAHs) using a USB camera. Akimitsu Kugimiya & Mohd Shafiq Nasir. pubs.rsc.org/ay/article/d...
front cover of issue 27 of Analytical Methods: The cover artwork depicts the pathway of PAHs from industrial and vehicular emissions to soil contamination. Following extraction from contaminated soil, PAHs are analyzed using a paper-based analytical device and quantified through smartphone enabling rapid, cost-effective, and accessible environmental monitoring.
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Analytical Methods @analyticalmethods.rsc.org · 13/07/2026
On the front cover of issue 26 of Analytical Methods: Synthetic blood-based infrared molecular fingerprints: artificial cohorts for methodological research. #OpenAccess from Niklas Leopold-Kerschbaumer, Nico Feiler and Kosmas V. Kepesidis Read now: pubs.rsc.org/ay/article/d...
front cover of issue 26 of Analytical Methods: Synthetic blood-based infrared fingerprints, generated using multivariate Gaussian models
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Analytical Methods @analyticalmethods.rsc.org · 06/07/2026
On the front cover of issue 25 of Analytical Methods: Direct inlet probe mass spectrometry with wavelength selective resonance enhanced photo ionisation. #OpenAccess from Christopher Paul Rüger et al. pubs.rsc.org/ay/article/d...
front cover of issue 25 of Analytical Methods:
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Analytical Methods @analyticalmethods.rsc.org · 29/06/2026
On the front cover of issue 24 of Analytical Methods: Real-time resonance Raman spectroscopic monitoring of the Briggs–Rauscher reaction. #OpenAccess from Royston Goodacre et al. Read now: pubs.rsc.org/en/content/a...
front cover of issue 24 of Analytical Methods: Conceptual image of online Raman spectroscopy being used to understand the Briggs-Rauscher oscillating reaction
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Analytical Methods @analyticalmethods.rsc.org · 22/06/2026
On the front cover of issue 23 of Analytical Methods: Pheromone measurement using secondary electrospray ionization and portable membrane inlet mass spectrometry. #OpenAccess from Stamatios Giannoukos et al. Read now: pubs.rsc.org/en/content/a...
front cover of issue 23 of Analytical Methods: Sensitive mass spectrometry reveals insect sex pheromones in real time, supporting smarter field monitoring and mating-disruption strategies
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Analytical Methods @analyticalmethods.rsc.org · 15/06/2026
On the front cover of issue 22 of Analytical Methods: Recovery of TNT from post-blast soil samples: effects of soil type, extraction methodology, and storage conditions. #OpenAccess from J. V. Goodpaster et al. Read now: pubs.rsc.org/en/content/a...
front cover of issue 22 of Analytical Methods
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Analytical Methods @analyticalmethods.rsc.org · 26/05/2026
On the front cover of issue 19 of Analytical Methods: A green analytical assay for the quantitation of bioavailable phosphorus in soils: in situ extraction and smartphone-based measurement. Arnaldo Alves Cardoso et al. pubs.rsc.org/en/content/a...
front cover of issue 19 of Analytical Methods
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Analytical Methods @analyticalmethods.rsc.org · 18/05/2026
On the front cover of issue 18 of Analytical Methods: Hydrogen-bond enhanced Tb/Eu-MOF for visual detection of multiple trace fluoroquinolones in seawater and a portable 3D-printed sensor. Fang Yuan et al. Read now: pubs.rsc.org/en/content/a...
front cover of issue 18 of Analytical Methods: The cover image depicts the detection of fluoroquinolone (FQ) antibiotics in seawater using a robust metal-organic framework (MOF)-based sensor. The artwork highlights the stability of the MOF architecture in the marine environment and illustrates the selective capture and sensing of FQ pollutants against an ocean backdrop.  
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Analytical Methods @analyticalmethods.rsc.org · 11/05/2026
On the front cover of issue 17 of Analytical Methods: An image-based food quality analysis framework driven by large language models. Xiao-Zhi Wang, Tong Wang et al. pubs.rsc.org/en/content/a...
front cover of issue 17 of Analytical Methods: A humanoid robot analyzes an image of an apple through a digital interface to reveal its food quality attributes. This image symbolizes a new LLM-based paradigm that can efficiently and without fine-tuning assess food quality directly from images through multimodal reasoning
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Analytical Methods @analyticalmethods.rsc.org · 06/05/2026
On the front cover of issue 16 of Analytical Methods: Beyond identification: inferring physical activity from fingerprint lipids using machine learning. #OpenAccess from Young Jin Lee et al. Read now: pubs.rsc.org/en/content/a...
front cover of issue 16 of Analytical Methods: A luminous blue fingerprint anchors interconnected icons representing physical activity, sedentary behavior, mass spectrometric lipid profiling, and machine learning, illustrating how fingerprint chemistry can be translated into physical activity classification through advanced analytical methods.
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Analytical Methods @analyticalmethods.rsc.org · 27/04/2026
On the front cover of issue 15 of Analytical Methods: Use of ATR-FTIR with D/H substitution for assessing water uptake in alkali perchlorate matrices. Sefik Suzer et al. pubs.rsc.org/en/content/a...
front cover of issue 15 of Analytical Methods: Water-alkali Metal Interoder
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Analytical Methods @analyticalmethods.rsc.org · 20/04/2026
On the front cover of issue 14 of Analytical Methods: Rapid in situ analysis of tobacco chemical composition via ultrasonic nebulization extraction coupled with atmospheric pressure photoionization mass spectrometry. Chengyuan Liu, Yang Pan, Bingjun Han et al. pubs.rsc.org/en/content/a...
front cover of issue 14 of Analytical Methods: The integration of ultrasonic nebulization extraction with dopant-assisted atmospheric pressure photoionization mass spectrometry enables rapid and sensitive in-situ analysis of endogenous compounds in complex tobacco matrices.
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Analytical Methods @analyticalmethods.rsc.org · 07/04/2026
On the front cover of issue 13 of Analytical Methods: A novel magnetic and fluorescent nanocomposite probe for detection of matrix metalloproteinase-2 in cells. Xianwei Zuo et al. pubs.rsc.org/en/content/a...
front cover of issue 13 of Analytical Methods: The magnetic-fluorescent nano-composite probe, self-assembling from the substrate peptide and magnetic beads, is used to detect MMP-2 via enzymatic cleavage.
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Analytical Methods @analyticalmethods.rsc.org · 30/03/2026
On the front cover of issue 12 of Analytical Methods: M-Count: an application that uses machine learning object detection and color thresholding to count settled mussel larvae. #OpenAccess from Curtis J. Larimer et al. pubs.rsc.org/en/content/a...
front cover of issue 12 of Analytical Methods: M-Count is an application that combines a neural network object detection model and a color thresholding algorithm to accurately count individual and grouped mussels in images of biofouling. The cover image illustrates the transformation from an image into quantified data.
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Analytical Methods @analyticalmethods.rsc.org · 23/03/2026
Our latest front cover: Adapting aqueous biphasic systems to solid-phase extraction for bioanalytical applications: high-abundance protein depletion and prostate-specific antigen extraction from human serum. #OpenAccess from Mara G. Freire, Francisca A. e Silva et al. pubs.rsc.org/en/content/a...
front cover of issue 11 of Analytical Methods
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Analytical Methods @analyticalmethods.rsc.org · 16/03/2026
On the front cover of issue 10 of Analytical Methods: A ratiometric FRET sensor using Ti3C2Tx MXene for intracellular microRNA-21 quantitative measurement. Tao Chen et al. pubs.rsc.org/en/content/a...
front cover of issue 10 of Analytical Methods
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Analytical Methods @analyticalmethods.rsc.org · 09/03/2026
On the front cover of issue 9 of Analytical Methods: Random forest models accurately classify synthetic opioids using high-dimensionality mass spectrometry datasets. #OpenAccess from Carolyn L. Fisher et al. Read now: pubs.rsc.org/en/content/a...
front cover of issue 9 of Analytical Methods: cover art shows how a machine learning meme translates to analytical chemistry. Much like how binary classification models can be trained to distinguish between photos
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Analytical Methods @analyticalmethods.rsc.org · 02/03/2026
On the front cover of issue 8 of Analytical Methods: Characterizing noninvasively conservation status of historical wet collections using spatially offset Raman spectroscopy. #OpenAccess from Wren Montgomery, Sara Mosca et al @arasfly3.bsky.social. Read now: pubs.rsc.org/en/content/a...
front cover of issue 8 of Analytical Methods: This cover weaves together two moments in time, with Charles Darwin studying preserved specimens, surrounded by countless jars. In the foreground, a hand-held Raman device scans a sealed jar, revealing the chemistry of its preservation fluids through the first non-invasive application of spatially offset Raman spectroscopy (SORS), offering a new way to assess and protect museum collections
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Analytical Methods @analyticalmethods.rsc.org · 23/02/2026
On the front cover of issue 7 of Analytical Methods: Revolutionizing biointerface analysis: nanoscale electrical insights from Kelvin probe force microscopy and their impact on biological science and industry. Haijian Zhong, Weidong Zhao et al. pubs.rsc.org/en/content/a...
front cover of issue 7 of Analytical Methods: This image illustrates the capability of KPFM to investigate the electrical properties of biological samples such as cells, DNA, viruses, and bacteria. The lightning on the tip and the halos around the samples represent their localized electrical charges.
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Analytical Methods @analyticalmethods.rsc.org · 18/02/2026
📢 Call for papers! Analytical Methods is launching a collection on Point‑of‑care diagnostics, focusing on paper devices, lab‑on‑chip, wearables, smartphone tools, advanced sensing & more! 📆Submit by 13 July 2026. Find out more 👉 blogs.rsc.org/ay/2026/02/1... #chemsky
A promotional banner for Analytical Methods featuring the theme “Point-of-care diagnostics” with a submission deadline of 13 July 2026. The background shows an abstract scientific image with soft, colorful light effects. Below the text, six rectangular profile images of different individuals are displayed, each with a name beneath: Stefano Cinti, Ningtao Cheng, Camellia Bala, Sevinc Kurbanoglu, Eden Morales-Narváez, and Waleed Alahmad. At the bottom left, the words “Submit now” appear, and at the bottom right is the Royal Society of Chemistry logo.
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Analytical Methods @analyticalmethods.rsc.org · 17/02/2026
Wishing you all a happy, healthy and prosperous #YearOfTheHorse🐎 🎆 To celebrate we’d like to share some of our most popular 2025 Analytical Methods articles by authors based in countries celebrating Lunar New Year and Chinese New Year 👇 pubs.rsc.org/en/Journals/...
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Analytical Methods @analyticalmethods.rsc.org · 16/02/2026
On the front cover of issue 6 of Analytical Methods: Adhesive tape for spatially resolved and sensitive detection of lead in dust using XRF. #OpenAccess from Marya Lieberman et al. Read now: pubs.rsc.org/en/content/a...
front cover of issue 6 of Analytical Methods
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Analytical Methods @analyticalmethods.rsc.org · 06/02/2026
On the front cover of issue 5 of Analytical Methods: Rapid quality assessment of organic fertilizers using fused FTIR and LIBS spectroscopy with machine learning. Changwen Du et al. pubs.rsc.org/en/content/a...
front cover of issue 5 of Analytical Methods
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Analytical Methods @analyticalmethods.rsc.org · 02/02/2026
On the front cover of issue 4 of Analytical Methods: Development of an HPV 16 rapid test founded in user-centered design with primary care clinicians. #OpenAccess from Jacqueline C. Linnes, Natalia M. Rodriguez et al @jlinnes.bsky.social Read now: pubs.rsc.org/en/content/a...
front cover of issue 4 of Analytical Methods: a rapid diagnostic test serving as a bridge between patients and the healthcare system
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Analytical Methods @analyticalmethods.rsc.org · 26/01/2026
On the front cover of issue 3 of Analytical Methods: Advances in MS-based glycomics for biomedical research. Yehia Mechref et al @ttu.edu pubs.rsc.org/en/content/a...
front cover of issue 3 of Analytical Methods: artwork depicts the glycomics workflow from cell surface glycoproteins through glycan release, ionization, and LC MS/MS detection, highlighting advances that bridge molecular glycan profiling with diagnostic and therapeutic applications.
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Analytical Methods @analyticalmethods.rsc.org · 19/01/2026
On the front cover of issue 2 of Analytical Methods: Recognition and separation of Gram-positive and Gram-negative bacteria using polythiophene derivatives with phosphonium groups. #OpenAccess from Yuko Takeoka et al. Read now: pubs.rsc.org/en/content/a...
front cover of issue 2 of Analytical Methods
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Analytical Methods @analyticalmethods.rsc.org · 15/01/2026
📢Check out our Open Call on Nanomaterials for Sensing in Analytical Methods, guest edited by Professor Beatriz Jurado-Sánchez, Professor Suban Kumar Sahoo, and Professor Itthipon Jeerapan. More info on how to submit can be found here👇: blogs.rsc.org/ay/2026/01/1...
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Analytical Methods @analyticalmethods.rsc.org · 12/01/2026
On the front cover of issue 1 of Analytical Methods: Single-fiber versus macroscale electrodes: enzyme loading and impacts on bioelectronic applications in flexible biodevices. Frank N. Crespilho et al. pubs.rsc.org/en/content/a...
Front cover of issue 1 of Analytical Methods
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Analytical Methods @analyticalmethods.rsc.org · 12/12/2025
On the front cover of issue 48 of Analytical Methods: Determination of volatile acids in sugarcane spirits exploring an air drag system and digital image photometry. Fabio R. P. Rocha. pubs.rsc.org/en/content/a...
Front cover of issue 48 of Analytical Methods.
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Analytical Methods @analyticalmethods.rsc.org · 08/12/2025
On the front cover of issue 47 of Analytical Methods: Lighting Up Zinc: Switchable Probes for Biological Imaging. #OpenAccess from Ozlem Dilek et al @ozlemdileklab.bsky.social @georgemasonu.bsky.social. Read now: pubs.rsc.org/en/content/a...
Front cover of issue 47 of Analytical Methods: Turn on imaging with zinc-sensing probes
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Analytical Methods @analyticalmethods.rsc.org · 01/12/2025
On the front cover of issue 46 of Analytical Methods: Automated dual-cartridge solid-phase extraction method for multi-residue determination of veterinary drugs in bovine muscle, liver, fat, and milk. Shizuka Saito-Shida et al. pubs.rsc.org/en/content/a...
Front cover of issue 46 of Analytical Methods: Illustrating a conceptual representation of an automated dual-cartridge SPE cleanup system designed for comprehensive multi-residue analysis of veterinary drugs.
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Analytical Methods @analyticalmethods.rsc.org · 24/11/2025
On the front cover of issue 45 of Analytical Methods: Transmission powder X-ray diffraction technique for precise identification and quantification of drug polymorphs – a case study using metformin embonate. Jagadeesh Babu Nanubolu et al. pubs.rsc.org/en/content/a...
Front cover of issue 45 of Analytical Methods: The cover image establishes the comparison of reflection and transmission X-ray diffraction geometries for polymorph analysis of API molecules, represented in the form of needles and block crystals in pharmaceutical capsule formulations. The background image also shows the atomic shells and X-ray generation via electronic transitions.
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Analytical Methods @analyticalmethods.rsc.org · 17/11/2025
On the cover of issue 44: Demonstrating the application of a liquid chromatography-mass spectrometry method for the determination of phthalate diesters in complex solid and liquid environmental samples. #OpenAccess from Fiona Regan et al @dublincityuni.bsky.social. pubs.rsc.org/en/content/a...
Front cover of issue 44 of Analytical Methods: Depiction of the sources, and receptors of phthalates and their methods of analysis in environmental samples.
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Analytical Methods @analyticalmethods.rsc.org · 10/11/2025
On the front cover of issue 43 of Analytical Methods: A liquid crystal-based sensor for real-time, selective, and visual detection of vanillin over coumarin in food samples. Sachin Kumar Singh et al. pubs.rsc.org/en/content/a...
Front cover of issue 43 of Analytical Methods.
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Analytical Methods @analyticalmethods.rsc.org · 03/11/2025
On the front cover of issue 42 of Analytical Methods: Simple preparation of an Au nanoparticle dispersed substrate by arc plasma deposition and its application in bio-sensing using LSPR. Takeshi Ito et al. pubs.rsc.org/en/content/a...
Front cover of issue 42 of Analytical Methods.
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Analytical Methods @analyticalmethods.rsc.org · 28/10/2025
📢 Welcome our newest Analytical Methods Advisory Board members: Dr. Stefano Cinti from the University of Naples, IT and Dr. Bob Pirok from the University of Amsterdam, NL. Please join us in welcoming Stefano and Bob to the Analytical Methods AB!🙌 #analyticalchemistry #biosensors #chromatography
A promotional graphic for analytical methods for the two new board members
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Analytical Methods @analyticalmethods.rsc.org · 27/10/2025
On the front cover of issue 41 of Analytical Methods: Nanoscale mapping of nucleolin–aptamer interactions on lung cancer cells reveals binding affinity hierarchy and spatial heterogeneity. Weidong Zhao, Feng Jiang et al. pubs.rsc.org/en/content/a...
Front cover of issue 41 of Analytical Methods. An aptamer functionalized AFM tip probing a cell membrane. The inset shows a close-up of the specific interaction between an aptamer and its target, nucleolin, a membrane protein.
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Analytical Methods @analyticalmethods.rsc.org · 20/10/2025
On the front cover of issue 40 of Analytical Methods: Considerations for deconvolution of oligonucleotide mass spectra in quality control. Michael Rühl. pubs.rsc.org/en/content/a...
Front cover of issue 40 of Analytical Methods. Image: Stream of oligonucleotide data leading to a mass spectrum.
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Analytical Methods @analyticalmethods.rsc.org · 13/10/2025
On the front cover of issue 39 of Analytical Methods: A protein-nanoparticle conjugate platform for simplified and sensitive protease activity assays. Masafumi Sakono et al. pubs.rsc.org/en/content/a...
Front cover of issue 39 of Analytical Methods. A schematic illustration of a protein–nanoparticle conjugate system for protease activity sensing, showing the cleavage-induced release of a luminescent protein.
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Analytical Methods @analyticalmethods.rsc.org · 06/10/2025
On the front cover of issue 38 of Analytical Methods: Comonomer distribution analysis of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)s using high-resolution MALDI-TOF mass spectrometry. Naoki Kanayama et al. pubs.rsc.org/en/content/a...
Front cover of issue 38 of Analytical Methods. The image highlights the capability of MALDI-spiral-TOF-MS in archiving exact mass analysis and advanced datamining of PHBH oligomers.
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Analytical Methods @analyticalmethods.rsc.org · 29/09/2025
On the front cover of issue 37 of Analytical Methods: Sustainable headspace-in-needle microextraction analysis of phthalates using biomass-derived carbon-coated needles. Sunyoung Bae and Jooyoung Kim. pubs.rsc.org/en/content/a...
Front cover of issue 37 of Analytical Methods. Image illustrates a sustainable headspace in-needlemicroextraction for detecting phthalates using biomass derived carbon coated needle.
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Analytical Methods @analyticalmethods.rsc.org · 23/09/2025
On the front cover of issue 36 of Analytical Methods: Identification of brazilein type B as a key marker for the presence of brazilwood in colored historical objects. #OpenAccess from Laura Hendriks et al. pubs.rsc.org/en/content/a...
Front cover of issue 36 of Analytical Methods. Cover picture: designed by Laura Hendriks with photos of an Italian 16th-century silk velvet fabric from the collection of the Abegg-Stiftung (inv. no. 239). Photos: © Abegg-Stiftung, CH-3132 Riggisberg, 2014 (Christoph von Viràg resp. Textile conservation studio). fabric from the collection of the Abegg-Stiftung (inv. no. 239). Photos: © Abegg-Stiftung, CH-3132 Riggisberg, 2014 (Christoph von Viràg resp. Textile conservation studio).
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