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Dr. Curmudgeon

@altgovdoc.altgov.info
35K followers 155 following 323 posts

General health and science information #medsky #emedsky Posts 🚫 med advice. Please, seek the care of your physician if you have any concerns.

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Dr. Curmudgeon @altgovdoc.altgov.info · 04/07/2026
Today is a day to remember a small group of people who wanted something better. People who were willing to fight for it. Those ideals are a thing of beauty. We love them and many new ones in our constant pursuit of freedom and justice for all. That’s what our flag represents. This is our flag.
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Dr. Curmudgeon @altgovdoc.altgov.info · 30/07/2025
While I know nothing about this case, this seems completely plausible, having unfortunately been present for a few of these.
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Dr. Curmudgeon @altgovdoc.altgov.info · 14/06/2025
👍🏻
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Dr. Curmudgeon @altgovdoc.altgov.info · 14/06/2025
I hope for the possibility while planning for the worst.
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Dr. Curmudgeon @altgovdoc.altgov.info · 13/06/2025
Yes. Herd immunity is when sufficient numbers of the population have been vaccinated against a disease in a timely fashion. Even their concept is null and void when viral mutations rapidly continue unabated and reinfection is the rule rather than exception.
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Dr. Curmudgeon @altgovdoc.altgov.info · 13/06/2025
Not having protective vaccines is profoundly serious. Your comment is concerning as you are making a choice to caste unnecessary dispersions that can be seen as an obtuse method for undermining extremely important information.
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Dr. Curmudgeon @altgovdoc.altgov.info · 13/06/2025
You will have some smaller amount of long term immunity ongoing and immediate response sort for 3-4 months before it begins to wane.
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Reposted by Dr. Curmudgeon
AltFDA @altfda.altgov.info · 13/06/2025
With tomorrow being #NoKingsDay, we have a unique opportunity to piss the other side off, to protect yourself and those around you. Wearing a mask at the marches and events does this. The bonus bonus affect is that it will also help mitigate the fall Covid boom! How the fuck about that?!?!
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Dr. Curmudgeon @altgovdoc.altgov.info · 13/06/2025
There is a NEJM address you may write to request printed corrections.
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Dr. Curmudgeon @altgovdoc.altgov.info · 13/06/2025
As the vaccines provide ≈3-4 months of immunity & there is a twice yearly increase in Covid, then the policy is the thing in error without regard to some US article announcing a devastating policy here that would prevent most from receiving any vaccine. But thank you for your generous input.
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Dr. Curmudgeon @altgovdoc.altgov.info · 13/06/2025
Devastating changes to vaccine policy will be catastrophic for the fall/winter flu and covid season. Last season 2500 covid deaths per week. There will likely be a significant increase Mask 😷 up, air quality, isolate when ill, spread the word, take care of each other www.nejm.org/doi/full/10....
nejm.org
An Evidence-Based Approach to Covid-19 Vaccination | NEJM
This article from the FDA compares broad U.S. recommendations on Covid vaccination with those from other countries and announces the adoption of an evidence-based approach to such recommendations.
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Dr. Curmudgeon @altgovdoc.altgov.info · 12/06/2025
Korea has some promising Pan-coronavirus vaccine research pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov
Pan‐Variant SARS‐CoV‐2 Vaccines Induce Protective Immunity by Targeting Conserved Epitopes
The development of a globally effective COVID‐19 vaccine faces significant challenges, particularly in redirecting the B‐cell response from immunodominant yet variable regions of viral proteins toward...
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Dr. Curmudgeon @altgovdoc.altgov.info · 12/06/2025
Ugh. NIH not NIG
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Dr. Curmudgeon @altgovdoc.altgov.info · 12/06/2025
This was promising research for a vaccine that would encompass the class of coronaviruses. The NIG grants for vax development are cancelled taggs.hhs.gov/Content/Data... www.nature.com/articles/s41...
nature.com
A trivalent protein-based pan-Betacoronavirus vaccine elicits cross-neutralizing antibodies against a panel of coronavirus pseudoviruses - npj Vaccines
npj Vaccines - A trivalent protein-based pan-Betacoronavirus vaccine elicits cross-neutralizing antibodies against a panel of coronavirus pseudoviruses
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Dr. Curmudgeon @altgovdoc.altgov.info · 12/06/2025
www.yalemedicine.org/news/novavax...
yalemedicine.org
Novavax's COVID-19 Vaccine: Your Questions Answered
The Novavax vaccine is one of three vaccines that are FDA-approved in the United States for the prevention of COVID-19. Yale Medicine answers commonly asked questions about the shot.
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Dr. Curmudgeon @altgovdoc.altgov.info · 02/06/2025
Males and females process pain through different brain pathways. Current pain management has been directed to how males process pain. This might also explain why females suffer more from chronic pain. pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov
Self-regulated analgesia in males but not females is mediated by endogenous opioids
Converging lines of preclinical and clinical research indicate that females, in stark contrast to males, display an increased prevalence of chronic pain. Females also demonstrate weaker analgesic effi...
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Dr. Curmudgeon @altgovdoc.altgov.info · 18/04/2025
Welcome! So pleased you are here.
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Dr. Curmudgeon @altgovdoc.altgov.info · 21/03/2025
Though you may have been told the pandemic is over, the virus does not care. It has one goal. To infect you and replicate. Please, remember your boosters, masks and air quality. Particularly for the summer and winter Covid seasons! 3/3 www.thelancet.com/journals/lan...
thelancet.com
Differences in Long COVID severity by duration of illness, symptom evolution, and vaccination: a longitudinal cohort study from the INSPIRE group
Among participants followed up to 3 years after initial infection, those with current Long COVID had worse physical and mental health outcomes. The majority of those with Long COVID did not resolve, w...
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Dr. Curmudgeon @altgovdoc.altgov.info · 21/03/2025
physical health, fatigue severity, physical activity, and dyspnea”. They did report some slight improvement in those with symptoms over 12 months. And importantly, those who were vaccinated with multiple boosters prior to infection had far better outcomes. 2/3
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Dr. Curmudgeon @altgovdoc.altgov.info · 21/03/2025
A prospective study in Lancet reveals 2% of those with Long Covid resolve, most have symptoms that continue at 2-3 years affecting their quality of life and mental health. “Long COVID-associated differences across multiple physical health outcomes, including overall 1/3
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Dr. Curmudgeon @altgovdoc.altgov.info · 17/03/2025
How are you staying healthy throughout this all?
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Dr. Curmudgeon @altgovdoc.altgov.info · 17/03/2025
Welcome to the fray @altusmc.bsky.social
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Dr. Curmudgeon @altgovdoc.altgov.info · 17/03/2025
Please, let me know what concerns you most at this time and how we can help us all weather through this.
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Dr. Curmudgeon @altgovdoc.altgov.info · 17/03/2025
Please, forgive my absence of late. PASC/Long Covid can really take over your life. Even missing the day set aside to recognize this very illness that has affected 1/20 Americans. Will be interested in bringing you updates concerning this as well as some of the other latest health issues of note.
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Dr. Curmudgeon @altgovdoc.altgov.info · 10/03/2025
Stanford has developed new antibody therapy for Covid effective against the non-mutating portions of the virus www.science.org/doi/10.1126/...
science.org
Bispecific antibodies targeting the N-terminal and receptor binding domains potently neutralize SARS-CoV-2 variants of concern
Bispecific antibodies incorporating a cross-reactive NTD-specific antibody are resilient to SARS-CoV-2 variants of concern.
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Dr. Curmudgeon @altgovdoc.altgov.info · 10/03/2025
media.tenor.com
Elvis Youre Too Kind GIF
ALT: Elvis Youre Too Kind GIF
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Reposted by Dr. Curmudgeon
AltSpaceForce 🚀🇺🇲 @altspaceforce.altgov.info · 01/03/2025
Thank you Doc. There are many "alt" accounts who haven't requested to join, have dropped out of vetting, some outright ghosted, and some who didn't make the cut. Stick with the starter pack. They're added immediately after vetting & have agreed to the standards for which #AltGov is known.
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Dr. Curmudgeon @altgovdoc.altgov.info · 01/03/2025
Some new folks have cleared the #AltGov verification and vetting process. See the official list at @altspaceforce.altgov.info In your enthusiasm for democracy, please also remember caution in these times. Disinformation has been and will be the greatest weapon.
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Dr. Curmudgeon @altgovdoc.altgov.info · 28/02/2025
A functional CDC, USAID, NIH and funded WHO.
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Dr. Curmudgeon @altgovdoc.altgov.info · 28/02/2025
iris.who.int/bitstream/ha...
iris.who.int
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Dr. Curmudgeon @altgovdoc.altgov.info · 28/02/2025
“What we know about the illnesses that have sickened over 400 people and killed more than 50 in Congo” medicalxpress.com/news/2025-02...
medicalxpress.com
What we know about the illnesses that have sickened over 400 people and killed more than 50 in Congo
Unidentified illnesses in northwestern Congo have killed more than 50 people over the past five weeks, nearly half of them within hours after they felt sick.
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Dr. Curmudgeon @altgovdoc.altgov.info · 25/02/2025
Having these management strategies is so very important when living with the chronic effects of this disease. There is a new study underway using ketamine protocols for this and other symptoms. The initial results are quite promising.
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Dr. Curmudgeon @altgovdoc.altgov.info · 23/02/2025
Predictors for sever Covid infections->age, chronic kidney disease, chronic obstructive pulmonary disease, Alzheimer's disease, heart failure, anaemia, and glucocorticoid use. www.thelancet.com/journals/ecl...
thelancet.com
Leveraging near-real-time patient and population data to incorporate fluctuating risk of severe COVID-19: development and prospective validation of a personalised risk prediction tool
Our novel risk prediction tool uses a simple method to adjust for temporal changes and can be implemented to facilitate uptake of evidence-based therapies. The study provides proof-of-concept for leve...
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Dr. Curmudgeon @altgovdoc.altgov.info · 23/02/2025
Long Covid effects on the brain have been numerous to include many new psychiatric symptoms. Anxiety, depression and even psychosis in patients without any previous underlying conditions or worsened when they do. www.thelancet.com/journals/ecl...
thelancet.com
First-Episode Psychosis incidence pre-, during, and post-COVID-19 pandemic: a six-year natural quasi-experimental study in South London
FEP incidence in South London increased during the peak of the COVID-19 pandemic, particularly among Black and Asian individuals.
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Dr. Curmudgeon @altgovdoc.altgov.info · 11/02/2025
Precisely the question. The NIH funded scientists developed the vaccine and federal funding procured the large doses to be made by pharmaceutical companies.
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Dr. Curmudgeon @altgovdoc.altgov.info · 10/02/2025
They have a human and other animal vax for this currently. mRNA vaccines can be made more quickly. Their efficacy vs traditional forms is under study.
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Dr. Curmudgeon @altgovdoc.altgov.info · 10/02/2025
More wise people out there than you realize my friend.
media.tenor.com
a close up of a statue of yoda smoking a cigarette with the word wise in the background .
ALT: a close up of a statue of yoda smoking a cigarette with the word wise in the background .
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Dr. Curmudgeon @altgovdoc.altgov.info · 09/02/2025
A thread about those who shy away from vaccinations 🧵
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Dr. Curmudgeon @altgovdoc.altgov.info · 09/02/2025
more often than not. Of course there are those whose minds cannot be moved. And the constant media drumming to not trust your physicians has made its permanent mark on our entire society that has led to much of this.
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Dr. Curmudgeon @altgovdoc.altgov.info · 09/02/2025
a lot of time and patience to hear and explore those emotions and experiences fully, find out what they would trust to carefully lead them to their own conclusions to obtain vaccinations in a way that fits them. Physicians rarely are accorded the time necessary for such a process. But it works
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Dr. Curmudgeon @altgovdoc.altgov.info · 09/02/2025
Having had long conversations with many of these, the predominant characteristic of their decision making is fear. Consumption of propaganda and lack of trusted sources for information. In the choice between data and fear, the more powerful motivator wins, fear wins. It takes
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Dr. Curmudgeon @altgovdoc.altgov.info · 09/02/2025
Continued ability to develop this H5N1 avian flu vaccine would be an important step. This would of course require continued funding of the science. www.nature.com/articles/s41...
nature.com
Development of a nucleoside-modified mRNA vaccine against clade 2.3.4.4b H5 highly pathogenic avian influenza virus - Nature Communications
Highly pathogenic avian influenza viruses from H5 clade 2.3.4.4b are circulating widely in birds and have recently caused large outbreaks in mammals. Here, Furey et al. develop a clade 2.3.4.4b HA-exp...
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Dr. Curmudgeon @altgovdoc.altgov.info · 09/02/2025
While understandably many feel this, we live together in a society that requires 95% be vaccinated to protect everyone from these horrible epidemics.
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Dr. Curmudgeon @altgovdoc.altgov.info · 09/02/2025
And you would benefit from knowing if you still remain immune. This wanes over time. You can have the levels of these antibodies checked to see if you would require vaccination to prevent infection.
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Dr. Curmudgeon @altgovdoc.altgov.info · 09/02/2025
www.npr.org/2023/07/25/1...
npr.org
Republicans' excess death rate spiked after COVID-19 vaccines arrived, a study says
After vaccines became widely available in 2021, "the excess death rate among Republican voters was 43% higher than the excess death rate among Democratic voters," Yale researchers say.
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Dr. Curmudgeon @altgovdoc.altgov.info · 08/02/2025
to the waves in the northeast. While most adults had vaccinations as children, immunity fades and boosters are needed. You can have your titers checked or just schedule a visit. Particularly those in contact with kids as they are the most common vector for infection spread.
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Dr. Curmudgeon @altgovdoc.altgov.info · 08/02/2025
Measles outbreak expands in West Texas around county with low vaccination rate | CNN Record numbers of children are not being vaccinated. You must have 95% to prevent epidemics. www.cdc.gov/schoolvaxvie... This is in addition
cdc.gov
Vaccination Coverage and Exemptions among Kindergartners
View national and state-level school vaccination coverage and exemption estimates.
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Dr. Curmudgeon @altgovdoc.altgov.info · 07/02/2025
I am so very sorry for your loss. The state of our care facilities is appalling. When and if you are ready, it would very much help others.
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Dr. Curmudgeon @altgovdoc.altgov.info · 06/02/2025
May I be so bold as to recommend a call to the CEO or Quality Management officer requesting a process improvement project for your formal complaint? Attaching the article from the pharmacist as well.
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Dr. Curmudgeon @altgovdoc.altgov.info · 06/02/2025
Good catch on your part. Exposing a failure in their system I hope was corrected. This is why I say knowing the variation from the patient’s dry or optimal weight is key.
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