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Alice Perucca

@aliperri.bsky.social
44 followers 43 following 8 posts

Biologist working in (cancer) mechanobiology - PhD student @ibecbarcelona.eu in Integrative Cell and Tissue Dynamics group Alumni @utrechtuniversity.bsky.social

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Alice Perucca @aliperri.bsky.social · 10/02/2025
7/7 Friends 🎈 I am incredibly grateful to have worked alongside my wonderful co-first author, @oriolmb.bsky.social. This project has been a surprising journey, filled with challenges, triumphs, and lots of laughs. Cheers to the friendships made through science!
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Alice Perucca @aliperri.bsky.social · 10/02/2025
4/7: MIRO enables high throughput testing of #immunotherapies, opening new possibilities for personalized cancer treatments. As a proof of concept, we restored anti-cancer immunity in resistant/immune-excluded HER2+ breast cancer with IL2 treatment. 💪 🎥 Immune cell migration upon treatment
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Alice Perucca @aliperri.bsky.social · 10/02/2025
3/7: Why MIRO is unique? ✅ Immunocompetent: tracks #ImmuneCells movement & interactions ✅ Cells self-organize & build their own extra-cellular matrix ✅ Cost-effective, reproducible & user-friendly 🎥 cellular organization in MIRO #ECM #TumorEcosystem
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Alice Perucca @aliperri.bsky.social · 10/02/2025
2/7: MIRO is an open fluidic device that models the tumour-stroma interface using patient-derived cells. This allows us to recreate aspects of the #TumorMicroenvironment and study immune cell interactions in the lab. 🔎🧫 #Microfluidics #OnChip
Left: 3D schematic representation of the cellular organisation in MIRO. Right: comparison between MIRO and patient sample cellular organization.
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