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Alessandra Carbone

@alecarbone.bsky.social
26 followers 9 following 7 posts

Computational Biology @sorbonneuniversite.bsky.social - Protein Sequences in Structure/Function/Classification, Genome Structure, Ancient Genomes & Geometry of Logical Reasoning

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Alessandra Carbone @alecarbone.bsky.social · 06/08/2026
What if protein language model embeddings could collaborate to reveal what proteins do and which residues determine their function? Applied to thioredoxins, visual opsins, cold-shock proteins from environmental diatoms in #TaraOceans. In bioRxiv: lnkd.in/eaAFAYJW #ProteinScience #MarineGenomics
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Alessandra Carbone @alecarbone.bsky.social · 24/07/2026
Our new results on PPI reconstructions are out! X-PAIR: an ultrafast multitask framework for proteome-scale reconstruction of PPI networks and partner-specific interfaces from sequence biorxiv.org/content/10.6... Retweet it. Great work with Sara Rescalli.
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Alessandra Carbone @alecarbone.bsky.social · 28/09/2025
We connected molecular signatures of selection with their mechanistic and functional relevance opening new ways of guiding experimental assays without requiring exhaustive testing of tens or hundreds of candidates. Read in Molecular Biology and Evolution: academic.oup.com/mbe/advance-...
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Alessandra Carbone @alecarbone.bsky.social · 20/02/2025
Designing a functional switch? We recoded a function of Chlamydomonas reinhardtii thioredoxin type-h into a photosynthetic type-f by switching selectivity determinants. Soon out in Frontiers in Plant Science: lnkd.in/emVPNHHa with Julien Henri, Stephane Lemaire, Gianluca Lombardi and Andrea Mancini.
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Alessandra Carbone @alecarbone.bsky.social · 08/02/2025
Diversifying disorders by distinguishing intrinsic and soft disorders, improves our understanding of proteins. See our new preprint on "LoRA-DR-suite: adapted embeddings predict intrinsic and soft disorder from protein sequences" - lnkd.in/esSD3qxq work done with Beatriz Seoane and Gianluca Lombardi
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Alessandra Carbone @alecarbone.bsky.social · 01/02/2025
Postdoc position on Al-Driven Discovery of Next-Gen Antibiotics. Join my team! Please, forward it. hashtag#AI hashtag#MachineLearningandAI hashtag#Artificialintelligence hashtag#MachineLearning hashtag#protein
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