Anish Simhal @aksimhal.bsky.social · 21/02/20256/ Interestingly, high WEE1 expression predicted worse PFS independently of other high-risk factors like MYC translocations, chromothripsis, TP53 deletion, and independent of treatment used! 100
Anish Simhal @aksimhal.bsky.social · 21/02/20254/ Using @themmrf.bsky.social CoMMpass dataset, we identified high-risk and low-risk groups based on WEE1 expression. Results? High WEE1 expression = significantly worse progression-free survival. 110