Department of Medical Biochemistry and Biophysics | 184 followers on LinkedIn. Driving Discovery in Biochemistry and Biophysics under the Northern Lights | Research at the Department of Medical Bioche...

Hsu et al. show that mitochondrial import blockage stress activates the ATP-dependent protease YME1L1, which degrades mitochondrial presequence translocase TIM23 subunits to promote cell growth.

The MBD2c splicing variant of MBD2 that is essential for nuclear transcription translocates to the mitochondria to regulate mitochondrial DNA transcription and respiration and is linked to drug resist...

imageimageThe human mitochondrial RNase Z complex is essential for the production of mitochondrial tRNAs. This study reveals its complete structural framework, detailing its role in tRNA maturation an...