iiinova — where your digital self keeps evolving

Ashley Frakes @afrakes.bsky.social · 18/03/2025

Happy to share a recent pre-print from our lab! Parental origin of transgene determines recombination efficiency in GFAP-CreERT2 mice www.biorxiv.org/content/10.1...

biorxiv.org

Parental origin of transgene determines recombination efficiency in GFAP-creERT2 mice

The Cre-loxP system is a powerful tool for spatial and temporal genetic manipulations. However, the system is prone to several limitations and caveats with respect to variable expression and recombina...

120