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Adam Simpkin

@adamsimpkin.bsky.social
35 followers 37 following 0 posts

Postdoc in Dan Rigden’s lab @ University of Liverpool, developing tools for CCP4. Passionate about enhancing computational methods for structural biology 🧬.

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Reposted by Adam Simpkin
Bioinformatics Advances @bioinfoadv.bsky.social · 17/07/2025
🔬 Just out in Bioinformatics Advances: "ABCFold: Easier running and comparison of AlphaFold 3, Boltz-1 and Chai-1"   Read the full paper here: doi.org/10.1093/bioadv/vbaf153 Authors include: @adamsimpkin.bsky.social, @danielrigden.bsky.social
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Reposted by Adam Simpkin
Daniel Rigden @danielrigden.bsky.social · 06/03/2025
Pleased to see our latest paper out in Acta Cryst D (journals.iucr.org/d/issues/202...). It describes Slice'N'Dice, software for splitting up an AlphaFold model (or any structure actually) in a variety of ways, and then placing it with Molecular Replacement or directly into a cryo-EM map.
journals.iucr.org
Slice'N'Dice: maximizing the value of predicted models for structural biologists
Recent advancements in computational structural modelling have provided structural biologists with access to high-quality predictions that can be used to aid experimental structure determination. Slic...
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