Sign in

Michael G. Ison, MD MS

@michaelisonmd.bsky.social
1.4K followers 619 following 84 posts

Transplant Infectious Diseases MD, clinical respiratory virologist and Editor-in-Chief of @TheTxIDJournal.bsky.social. All opinions and tweets are my own.

PostsRepliesMedia
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 12/08/2026
Join in on our next CPC - focusing on potential ID challenges of transplant tourism! Wed Sept 2 @ 7am EST, 2pm Riyadh A great interactive case discussion with expert education. @bradgardiner.bsky.social @kottonnelson.bsky.social @tidsection.bsky.social tts.org/component/co...
031
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 27/05/2026
It’s pretty standard practice and great move for transparency.
020
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 26/05/2026
Many have wanted the data - and the final publication for the Nitazoxanide for Norovirus in Transplants Study is out! Time to stop using nitazoxanide for norovirus - zero impact on virology, no impact on clinical outcomes and clear financial toxicity. pubmed.ncbi.nlm.nih.gov/42177030/
pubmed.ncbi.nlm.nih.gov
A Phase 2 Multi-Center, Prospective, Randomized, Double-Blind Study to Assess the Clinical and Antiviral Efficacy and Safety of Nitazoxanide for the Treatment of Norovirus in Hematopoietic Stem Cell a...
Norovirus (NoV) may cause or contribute to chronic diarrhea among immunocompromised hosts. Neither vaccines nor antiviral therapies are available to prevent or treat NoV. We conducted an NIH-sponsored...
163
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 23/04/2026
ESGICH is trying to learn about what local/regional Immunocompromised Host ID Networks that hold meetings to share challenging cases or other info. If you participate in these or don’t have access to one and would want to - please complete the survey. forms.gle/jTUoweU1ebu8...
forms.gle
ESGICH Local or Regional Immunocompromised ID Networks Survey
Having forums to discuss challenging cases or novel approaches to the diagnosis and treatment of infections in immunocompromised patients are critical. There are a number of local and regional networ...
021
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 30/03/2026
On behalf of the TID section of TTS, ESGICH and the @thetxidjournal.bsky.social we invite you to: ESGICH – CPC Webinar: Thursday, April 9, 2026, at 14:00 CET

A Neglected Tropical Disease Beyond Endemic Borders: A Case-Based Discussion Registration link: us06web.zoom.us/webinar/regi...
040
Reposted by Michael G. Ison, MD MS
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 21/03/2026
Submit Ideas for Potential ESGICH Sessions at ESCMID Global 2027: If you have ideas for sessions, even if attend the in person meeting, please submit the ideas online . You can submit ideas by close of business April 17 via this link: forms.gle/ecb4ZrJkK9F3... 3/3
forms.gle
ESGICH ESCMID Global 2027 Session Concept Submission Form
Please use this form for ideas for sessions at ESCMID Global 2027. These must be submitted by April 17, 2026 5pm CET so that we can discuss them at our in person/Zoom planning meeting.
011
Reposted by Michael G. Ison, MD MS
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 21/03/2026
Participate in the Session Brainstorming Session: Sunday April 19 at 10:30am – 12:30pm in ICM 2nd Floor, Ostersee Room. A Zoom link will be shared shortly. If you want to participate in this session, please sign up using this link: forms.gle/vNnPYFuifXUH... 2/3
forms.gle
ESGICH Planning Committee for 2027 ESCMID Global
This will be a small working group to help develop proposals for ESGICH to propose for the 2027 ESCMID Global Program. The group will brainstorm in person at ESCMID Global in Munich: Sunday April 1...
121
Reposted by Michael G. Ison, MD MS
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 21/03/2026
ESGICH is seeking help in developing proposals for @escmid.bsky.social Global 2027. We are seeking participation in a brainstorming session in Munich April 19 10:30am - 12:30pm in Ostersee Room, 2nd Floor of the ICM. We are also seeking ideas for sessions. See next tweets w/ details 1/3
132
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 21/03/2026
Submit Ideas for Potential ESGICH Sessions at ESCMID Global 2027: If you have ideas for sessions, even if attend the in person meeting, please submit the ideas online . You can submit ideas by close of business April 17 via this link: forms.gle/ecb4ZrJkK9F3... 3/3
forms.gle
ESGICH ESCMID Global 2027 Session Concept Submission Form
Please use this form for ideas for sessions at ESCMID Global 2027. These must be submitted by April 17, 2026 5pm CET so that we can discuss them at our in person/Zoom planning meeting.
011
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 21/03/2026
Participate in the Session Brainstorming Session: Sunday April 19 at 10:30am – 12:30pm in ICM 2nd Floor, Ostersee Room. A Zoom link will be shared shortly. If you want to participate in this session, please sign up using this link: forms.gle/vNnPYFuifXUH... 2/3
forms.gle
ESGICH Planning Committee for 2027 ESCMID Global
This will be a small working group to help develop proposals for ESGICH to propose for the 2027 ESCMID Global Program. The group will brainstorm in person at ESCMID Global in Munich: Sunday April 1...
121
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 21/03/2026
ESGICH is seeking help in developing proposals for @escmid.bsky.social Global 2027. We are seeking participation in a brainstorming session in Munich April 19 10:30am - 12:30pm in Ostersee Room, 2nd Floor of the ICM. We are also seeking ideas for sessions. See next tweets w/ details 1/3
132
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 02/03/2026
3 years ago, I was in the Community of Leaders group and can say it had such a huge impact on how I lead - I recommend this to anyone who wants to be a more engaged and effective leader! Time well spent!
000
Reposted by Michael G. Ison, MD MS
Erik Karlsson @eakarlsson.bsky.social · 14/02/2026
First human #H5N1 case of 2026 in #Cambodia: a 30-year-old man from Kampot province. Sequencing, virus isolation & animal investigations ongoing. Dead chicken at home before onset. Patient has since recovered. 🦠💉😷🐓🥼🔬🧪 Sequencing, contact tracing, and poultry investigations ongoing.
11512
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 12/02/2026
Not surprisingly, most adults healthcare-associated respiratory virus infections are immunocompromised and they account for the sickest patients. A key signal to better protect our most vulnerable patients. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Hospital‐Acquired Respiratory Viral Infections (HA‐RVIs) Over 10 Years Disproportionally Affect the Immunocompromised
The incidence of HA-Flu/RSV/PIV is associated with patients at high risk of developing RVI complications such as oncology and SCT patients and that most HA cases occur during winter respiratory virus...
043
Reposted by Michael G. Ison, MD MS
Jon Cohen @cohenjon.bsky.social · 23/01/2026
www.science.org/content/arti...
science.org
Bird flu antibodies found in cow in the Netherlands, a first outside of U.S.
Dead cat led to discovery, but officials stress no further spread of H5N1 has been detected
01212
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 12/12/2025
But worth it for piece of mind.
020
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 12/12/2025
It’s actually hard to get the vaccine - we got ours but it required pre-paying for the doses and having delays in getting them delivered to the pharmacy. Total cost $900 with GoodRx and 3 doses so takes time. Doable but expensive and takes a lot of effort to arrange (in my experience).
130
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 25/11/2025
So happy to see this paper out after a lot of persistence from Shardul Rathod @hannahnam.bsky.social @ucirvine.bsky.social. Over a 10 yr period, 6.6% of Flu cases, 12.2% of RSV cases, and 10.9% of PIV cases were Hosp-Acquired. Most in ICH. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Hospital‐Acquired Respiratory Viral Infections (HA‐RVIs) over 10 Years Disproportionally Affect the Immunocompromised
The incidence of HA-Flu/RSV/PIV is associated with patients at high risk of developing RVI complications such as oncology and SCT patients and that most HA cases occur during winter respiratory virus...
061
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 15/11/2025
I had the HUGE honor of being the 40th Forbes Fellow - when I was the previous awardees, I was truly humbled. The ID community is incredible in Melbourne. @monashuniversity.bsky.social @unimelb.bsky.social @thedohertyinst.bsky.social @trubianojason.bsky.social @bradgardiner.bsky.social
1122
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 22/10/2025
Important Ongoing Studies where we have or will have publications soon: Pritelivir for refractory or resistant HSV (presented @idweek.bsky.social by @kottonnelson.bsky.social): www.aicuris.com/press-releas... CD388 for prevention of influenza: www.cidara.com/news/cidara-...
aicuris.com
Aicuris Announces Pritelivir Met Primary Endpoint in Immunocompromised Herpes Simplex Virus-infected Patients in Phase 3 Pivotal Trial - Aicuris
Aicuris today announced that the Phase 3 trial of its lead candidate pritelivir has met its primary and secondary endpoint. The aim of the trail was to evaluate
062
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 22/10/2025
Results from season 3 of the GSK RSV Vaccine (NOTE - I was the lead author so I’m biased on this one) www.thelancet.com/journals/lan... Two trials on tecovirimat for Mpox and the need to consider research in context of EUA medications www.nejm.org/doi/full/10.... evidence.nejm.org/doi/full/10....
thelancet.com
Efficacy, safety, and immunogenicity of the AS01E-adjuvanted respiratory syncytial virus prefusion F protein vaccine (RSVPreF3 OA) in older adults over three respiratory syncytial virus seasons (AReSV...
A single RSVPreF3 OA dose was efficacious against RSV-LRTD over three RSV seasons in people aged 60 years or older, despite a decrease in efficacy over time. Further research is needed to establish th...
142
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 22/10/2025
Study of baloxavir to prevent household transmission of influenza www.nejm.org/doi/full/10.... Two studies of monoclonals for RSV prevention www.nejm.org/doi/full/10.... www.thelancet.com/journals/lan...
nejm.org
Efficacy of Baloxavir Treatment in Preventing Transmission of Influenza | NEJM
Baloxavir marboxil (baloxavir) rapidly reduces influenza virus shedding, which suggests that it may reduce transmission. Studies of treatment with neuraminidase inhibitors have not shown sufficient...
121
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 22/10/2025
Two trials on lenacapravir for prevention of HIV www.nejm.org/doi/full/10.... www.nejm.org/doi/10.1056/... Two trials on high dose influenza vaccine jamanetwork.com/journals/jam... www.nejm.org/doi/abs/10.1... www.nejm.org/doi/abs/10.1...
nejm.org
Twice-Yearly Lenacapavir for HIV Prevention in Men and Gender-Diverse Persons | NEJM
Twice-yearly subcutaneous lenacapavir has been shown to be efficacious for prevention of human immunodeficiency virus (HIV) infection in cisgender women. The efficacy of lenacapavir for preexposure...
152
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 22/10/2025
Due to the USG Shutdown, I wasn’t able to attend or present @idweek.bsky.social. I was supposed to give the talk on top viral studies that will impact your practice. Here are the papers I was going to highlight: See next posts
53514
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 21/10/2025
Thanks to Lara Danziger-Isakov for doing the talk. Slides: www.dropbox.com/scl/fi/nj1z8...
dropbox.com
050
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 21/10/2025
Due to the US Government Shutdown, I will not be able to atted @IDWeek.bsky.social #IDWeek2025. I had worked on my 2 invited talks and so will share them. My first talk was going to be about the epidemiology and clinical course of respiratory viral infections in the immunocompromised.
1132
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 20/10/2025
Included in the supplement is an important paper about application of antivirals in immunocompromised patients @mady247.bsky.social academic.oup.com/jid/article/...
academic.oup.com
Influenza Antivirals for Prevention and Treatment in Immunocompromised People
Antivirals are an important backbone for the prevention and treatment of influenza in immunocompromised individuals, who are prone to prolonged viral shedd
031
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 20/10/2025
Excited to see the “Advances in Influenza Therapeutics” supplement out in @jidjournal.bsky.social - led by Fred Hayden and Rich Whitley, this supplement reviews what we know about antivirals and how they should be used for influenza. academic.oup.com/jid/issue/23...
academic.oup.com
Volume 232 Issue Supplement_3 | The Journal of Infectious Diseases | Oxford Academic
An official journal of the Infectious Diseases Society of America. Publishes research results on microbiology, immunology, and epidemiology; pathogenesis, diagnosis, and treatment of infectious diseas...
153
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 26/09/2025
Do you focus on HSCT/Oncology ID? Want to be part of the editorial team of @thetxidjournal.bsky.social? Please apply by October 17 for an open position as outlined in this link!
181
Reposted by Michael G. Ison, MD MS
Brad Gardiner @bradgardiner.bsky.social · 03/09/2025
check out our review of donor-derived infections in heart & lung transplant recipients! was a pleasure working with @michaelisonmd.bsky.social on this! #TxID doi.org/10.1016/j.jh...
doi.org
Redirecting
041
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 17/09/2025
The ISRV AVG meeting kicked of by Fred Hayden giving the 2nd Roberts/Tisdale lecture on the clinical implications of antiviral resistance.
260
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 15/08/2025
Excited to have this paper out! Demonstrates that the recipients of lung 🫁 tx for COVID-Associated Lung Injury (CALI) loose humoral protection and have unique cellular immune responses. www.sciencedirect.com/science/arti...
sciencedirect.com
Identification of immune signatures associated with both SARS-CoV-2 infection and lung transplantation
Lung transplantation (lung-tx) offers the last life-saving option for patients with COVID-19-associated lung injury (CALI). We show that the RBD-speci…
031
Reposted by Michael G. Ison, MD MS
American Journal of Transplantation @amjtransplant.bsky.social · 10/07/2025
AJT’S new ID blog, TxIDExchange, is dedicated to sharing the latest ID updates, research, and guidelines relevant to the transplant community. We’re soliciting blog posts and comments from you and your colleagues and encourage you to participate. ajt-transplant-id-exchange.squarespace.com
098
Reposted by Michael G. Ison, MD MS
Joanna Schaenman, MD, PhD @jschaenmanmd.bsky.social · 03/08/2025
Don't miss the new @amjtransplant.bsky.social #TxID blog led by Emily Blumberg ajt-transplant-id-exchange.squarespace.com #wtc2025 @ast-idcop.bsky.social @ast-tyfcop.bsky.social @astinfo.bsky.social
ajt-transplant-id-exchange.squarespace.com
AJT Transplant ID Exchange
0136
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 01/08/2025
Excited to head to San Francisco for #WTC2025 @ast-idcop.bsky.social
0120
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 14/05/2025
Michael Woodward presented on utility of FMT in ICHs - can reduce risk of recurrent C diff and MDRO infections - cost, availability and lack of guidance are limiting application @fredhutch 5th Symposium on ID in ICHs. www.science.org/doi/10.1126/...
1131
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 14/05/2025
Likewise, screening for FQ resistance may inform what breakthrough infections will occur and optimize early management.
020
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 14/05/2025
Mike Satlin gave an incredible review of MDR-GBR. These challenging bacteria cause freq infections and screening for can inform management of F&N @fredhutch.bsky.social 5th Symposium on ID in ICHs.
2111
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 14/05/2025
Jay Fishman provided the keynote on Xenotransplantation- major progress but many unknowns- thankfully formal clinical trials will help inform optimal approach @fredhutch.bsky.social 5th Symposium on ID in ICHs.
061
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 13/05/2025
Erika Kampouri provided a masterful review of infections after CAR-T and the impact of CMV and HHV6 in these patients - HHV6 CNS disease rare, CMV needs more data to confirm optimal management. @fredhutch.bsky.social 5th Symposium on ID in ICHs onlinelibrary.wiley.com/doi/10.1111/...
1132
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 13/05/2025
The future may be using the tool to look at pathogen and host response in the same assay - multiple examples shown that the combined approach provided answers that wouldn’t have been identified.
140
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 13/05/2025
Charles Chiu @UCSF gave an amazing lecture on mNGS in immunocompromised- while helpful, limitations exist and must be recognized to interpret the results.
162
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 12/05/2025
Amazing talk on aging and infection Maheen Abidi - many questions and need for data to inform management approaches. @fredhutch.bsky.social Symposium of Infections in ICH
070
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 12/05/2025
Hans Hirsch provided a master class in BKV as the keynote for the 5th @fredhutch.bsky.social Symposium on Infections in ICH. Studies have advanced our understanding of pathogens and management - but many questions remain.
163
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 12/05/2025
Michael Boeckh highlights the grow of the the @fredhutch Symposium on Infections - matching interest the field of #TxID It’s easy to see why with an expansion of tools to study and apply to improve outcomes in our patients!
1112
Reposted by Michael G. Ison, MD MS
ID Chief @ UMich @adamlauring.bsky.social · 23/04/2025
Really excited to be a part of this study and see it published today! Efficacy of Baloxavir Treatment in Preventing Transmission of Influenza | New England Journal of Medicine www.nejm.org/doi/full/10....
nejm.org
Efficacy of Baloxavir Treatment in Preventing Transmission of Influenza | NEJM
Baloxavir marboxil (baloxavir) rapidly reduces influenza virus shedding, which suggests that it may reduce transmission. Studies of treatment with neuraminidase inhibitors have not shown sufficient...
25314
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 16/04/2025
Adjuvanted RSV profusion F vaccine protection over 3 years - while VE declined over time, there remains significant protection against severe disease. More data is needed for longer term outcomes to inform optimal use.
041
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 12/04/2025
It was an honor to review the data on the link between Ureaplasma spp and Hyperammonemia in Lung Transplant recipients @ESCMID #ESCMIDGlobal 2025. Slides are here for those who want them. www.dropbox.com/scl/fi/ei4ym...
dropbox.com
0102
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 12/04/2025
A true master class on Chagas in transplantation - emerging data supports the safety of using Chagas positive donors with careful monitoring and treatment. Marcelo Radisic #ESCMIDGlobal
051
Michael G. Ison, MD MS @michaelisonmd.bsky.social · 12/04/2025
Great review of TB in endemic regions including approaches to use universal prophylaxis to reduce the incidence of post-transplant infection. @RubinaNaqvi1
010