iiinova — where your digital self keeps evolving

CORE IM @coreimpodcast.bsky.social · 19/11/2025

6/ Thanks to all for this great learning! By: @shreyatrivedimd.bsky.social Dr. Alice Kennedy Dr. Ross Prager Graphic: Dr. Alice Kennedy Audio: Xi Park

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CORE IM @coreimpodcast.bsky.social · 19/11/2025

1/ 🚨 NEW episode on venous congestion & the VExUS score 💧 Venous congestion is a century-old concept, but modern tools now allow clinicians to detect, quantify, and monitor it ‼️ 🖥️: www.coreimpodcast.com/2025/11/19/v...

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CORE IM @coreimpodcast.bsky.social · 05/11/2025

5/ Thanks to all for diving into this debate on diabetes drugs! Authors: @shreyatrivedimd.bsky.social, Dr. Tracy Rabin, Dr. Kenneth Fifer and Dr. Cary Blum Graphic: Amy Mu Audio: Kathreene Gala

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CORE IM @coreimpodcast.bsky.social · 05/11/2025

1/ 🚨 NEW episode on first line meds for Type 2 DM ‼️ Let’s dive in and discuss whether tried and true metformin vs. newer options, like SGLT2i or GLP1RA, are better for YOUR patient 🌊 🖥️: www.coreimpodcast.com/2025/11/05/d...

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CORE IM @coreimpodcast.bsky.social · 29/10/2025

2/ Thanks, Dr. Stephen Cooper!

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CORE IM @coreimpodcast.bsky.social · 29/10/2025

1/ 🚨 NEW video on Lp(a) ‼️ Let’s review what it is, who should be screened, and what we can do about it if it’s elevated 🎥: www.youtube.com/watch?v=lKkf... Behind the scenes: www.youtube.com/watch?v=Xh9L... 🖥️: www.coreimpodcast.com/2025/04/02/l...

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CORE IM @coreimpodcast.bsky.social · 28/10/2025

TRUE ‼️ Use this handy chart to remember conversions and glucocorticoid/mineralocorticoid activity of steroids! www.coreimpodcast.com/2023/06/28/s...

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CORE IM @coreimpodcast.bsky.social · 22/10/2025

1/ 🚨 NEW #5Pearls: Hepatorenal Syndrome Part ✌️ Let’s dive into treatment 🌊! 1️⃣ Vasoconstrictors 2️⃣ Albumin 3️⃣ Diuretics Goal: raise MAP by 10-15 ‼️ 🖥️: www.coreimpodcast.com/2025/10/22/h...

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CORE IM @coreimpodcast.bsky.social · 15/10/2025

1/ 🚨 NEW #5Pearls: Hepatorenal Syndrome (HRS) part 1️⃣ AKI + portal HTN 🟰hepatorenal syndrome 🖥️: www.coreimpodcast.com/2025/10/15/h...

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CORE IM @coreimpodcast.bsky.social · 14/10/2025

Answer: YES Review the REVISE trial w/ @NEJMGroup below ⤵️ www.coreimpodcast.com/2024/12/11/s...

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CORE IM @coreimpodcast.bsky.social · 01/10/2025

8/ Thanks to all for breaking (pun-intended) this down! By: Dr. Sarah Gorey, Dr. Clem Lee Dr. Greg Katz and @shreyatrivedimd.bsky.social Experts: Dr. Annie Garment and Dr. Ole-Petter R. Hamnvik Graphic: Dr. Jimin Hwang Audio: Kathreene Gala RN

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CORE IM @coreimpodcast.bsky.social · 01/10/2025

1/ 🚨 NEW #BeyondJournalClub w/ @NEJMGroup: The Bolland study Question: Does infrequent zoledronate therapy in patients without osteoporosis prevent fractures? Answer: ⤵️ www.coreimpodcast.com/2025/10/01/b...

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CORE IM @coreimpodcast.bsky.social · 16/09/2025

1/ 🚨 NEW #WhiteboardAnimation: ILD 🫁 Let’s talk ILD classification & management ⤵️ 🎥: www.youtube.com/watch?v=GjBg... 🖥️: www.coreimpodcast.com/2025/09/14/i...

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CORE IM @coreimpodcast.bsky.social · 11/09/2025

5/ There are some non-pharmacologic ways to manage orthostatic hypotension ‼️ ✨ Hydrate ✨ Compression ✨ Mobility 🛑 Avoid standing quickly 🛑Avoid high carb meals 🛑 Don’t forget to address culprit meds!

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CORE IM @coreimpodcast.bsky.social · 11/09/2025

4/ Signs of neurogenic: ✨ Insufficient heart rate response upon standing ✨ Comes on after a delay of 5+ minutes (early disease) ✨ Comes suddenly (late disease) ✨ Concomitant symptoms of neurogenic/autonomic disease

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CORE IM @coreimpodcast.bsky.social · 11/09/2025

1/ 🚨 NEW #GrayMatters: Orthostatics part 1️⃣ Orthostatic hypotension is VERY common ‼️ ✨ 20% of those over 60 years old ✨ 50% in nursing homes Causes: ✨ Decreased venous return ✨ Neurogenic 🖥️: www.coreimpodcast.com/2025/09/11/o... Sponsor: Oakstone CME

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CORE IM @coreimpodcast.bsky.social · 11/09/2025

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CORE IM @coreimpodcast.bsky.social · 11/09/2025

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CORE IM @coreimpodcast.bsky.social · 11/09/2025

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CORE IM @coreimpodcast.bsky.social · 04/09/2025

#TBT to our #BeyondJournalClub episode on RSV vaccine trials 💉 Takeaway: Abrysvo and Arexvy seem protective with reassuring side effect profiles BUT true efficacy difficult to discern with small number of RSV cases in both trials 🖥️: www.coreimpodcast.com/2024/01/31/r...

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CORE IM @coreimpodcast.bsky.social · 03/09/2025

3/ Thanks to all: Author: Tom Mulvey Editor: Marissa LoCastro

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CORE IM @coreimpodcast.bsky.social · 03/09/2025

1/ 🚨 NEW #ReadingRoom: Extra-axial bleeds 🩸 Part 1: Let’s review CT head findings for epidural, subdural, and subarachnoid bleeds!

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CORE IM @coreimpodcast.bsky.social · 20/08/2025

1/ 🚨 NEW #WhiteboardAnimation: COPD Classification (GOLD guidelines simplified) This classification system takes into account spirometry and symptoms to guide treatment 🫁 💨 🎥: www.youtube.com/watch?v=NJLZ... 🖥️: www.coreimpodcast.com/2025/08/20/c...

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CORE IM @coreimpodcast.bsky.social · 13/08/2025

10/ Thanks to all! By: @shreyatrivedimd.bsky.social, Dr. Casey Kim, Experts: Dr. Eric Bow, Dr. Lauren Merz and Dr. Jason Freed Graphic: Dr. Jesse Powell

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CORE IM @coreimpodcast.bsky.social · 13/08/2025

9/ First line treatment: 🦠 Antipseudomonal antibiotic Vanco is NOT considered standard of care, but added in specific scenarios 🦠 Hemodynamic instability 🦠 Known MRSA colonization AND infection source likely MRSA Maybe anti-fungal if >3 days of ANC < 200 + context 🤔

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CORE IM @coreimpodcast.bsky.social · 13/08/2025

6/ Neutrophil recovery time depends on the cause‼️ 🦠 10-14 days: Viral infections and immune mediated drug neutropenia 🦠 3-4 weeks: Dose dependent drug neutropenias 🦠 Variable: Autoimmune diseases & myelodysplastic syndromes (MDS)

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CORE IM @coreimpodcast.bsky.social · 13/08/2025

3/ 🦠 Patients with Duffy Null have ⬇️ peripheral neutrophil counts but completely normal total body neutrophil counts & immune function 🦠 Neutrophils sequester in the spleen as opposed to the peripheral blood

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CORE IM @coreimpodcast.bsky.social · 13/08/2025

1/ 🚨 NEW #5Pearls: Neutropenia 🦠 Let’s review the what, when, and why of neutropenia, including management of febrile neutropenia 🥵 🖥️: www.coreimpodcast.com/2025/08/13/n...

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CORE IM @coreimpodcast.bsky.social · 07/08/2025

#TBT to our #5Pearls episode: rhythm control in AFib The anti-arrythmics can be confusing, but this table breaks down the basics ‼️ 🖥️: www.coreimpodcast.com/2024/04/24/r...

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CORE IM @coreimpodcast.bsky.social · 06/08/2025

1/ 🚨 NEW #BehindTheScenesInterviews: Pleural Effusions 🖥️: www.coreimpodcast.com/2025/08/06/p... 🎥: youtube.com/playlist?lis...

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CORE IM @coreimpodcast.bsky.social · 28/07/2025

2/ Thanks to all for this resonating episode! Hosts: Dr. Marissa LoCastro @shreyatrivedimd.bsky.social Discussant: Dr. Maria Rosasco Editor: Kathreene Gala

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CORE IM @coreimpodcast.bsky.social · 28/07/2025

1/ 🚨 NEW #StoriesForTheFeels In the midst of burnout and inboxes, this episode is a breath of fresh air 💨 Dr. Rosasco shares three stories remind us that showing up as a human is still part of the job🤍 🖥️ : www.coreimpodcast.com/2025/07/28/s... Sponsor: Oakstone CME ACP MKSAP Companion

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CORE IM @coreimpodcast.bsky.social · 21/07/2025

1/ 🚨 NEW #Hoofbeats episode! Let’s diagnose BOTH the patient and the clinician by figuring out the disease process and the cognitive processes that led us towards/away from it 🩺 🖥️: www.coreimpodcast.com/2025/07/21/d...

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CORE IM @coreimpodcast.bsky.social · 15/07/2025

#TriviaTuesday Urine osmolality is a window into which hormone’s activity? Review hyponatremia diagnostics and use this graphic on the wards! www.coreimpodcast.com/2021/02/10/5...

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CORE IM @coreimpodcast.bsky.social · 09/07/2025

9/ Thanks to all ‼️ By: @shreyatrivedimd.bsky.social, Dr. Kalaila Pais, Dr. Christopher Kapp, Dr. David Furfaro and Dr. Kristina Montemayor Graphic: Dr. Jesse Powell Peer Review: Dr. Kanupriya Soni, Dr. Laura McNamara, Dr. Michael Ferrera, Mihir Parikh

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CORE IM @coreimpodcast.bsky.social · 09/07/2025

3/ Transudative: ⬆️ hydrostatic and ⬇️ oncotic pressure 🌊 Heart failure 🌊 Renal failure 🌊 Liver failure Exudative effusions: ⬆️ capillary permeability allowing complex materials to enter the pleural space 🌊 Infxn 🌊 Malignancy 🌊 PE

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CORE IM @coreimpodcast.bsky.social · 09/07/2025

1/ 🚨 NEW #5Pearls: Pleural Effusions 🌊 Did you know up to 30% of pleural effusions of have more than one etiology? Let’s dive in! 🖥️: www.coreimpodcast.com/2025/07/09/p... Sponsor: Oakstone CME Featuring: @pulmpeeps.bsky.social

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CORE IM @coreimpodcast.bsky.social · 02/07/2025

3/ 3/ Thanks to all for sharing these stories! Hosts: Marissa LoCastro, @shreyatrivedimd.bsky.social Discussants: George Tran, Allie Trainor Audio: Kath Gala

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CORE IM @coreimpodcast.bsky.social · 02/07/2025

1/ 🚨 NEW: July stories 3.0 🩺 Listen for some good laughs and memorable stories as a humble reminder for mixed emotions and experiences the transition can bring! 🖥️: www.coreimpodcast.com/2025/07/02/j...

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CORE IM @coreimpodcast.bsky.social · 25/06/2025

8/ Thanks to all! Authors: Chris Kotanidis, Clem Lee, @shreyatrivedimd.bsky.social , Greg Katz Graphics: Jimin Hwang Peer Reviewer: Jane Leopold

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CORE IM @coreimpodcast.bsky.social · 25/06/2025

7/ REDUCE-AMI found no benefit from routine beta blocker initiation in post-MI patients with preserved ejection fraction, challenging a longstanding default approach in cardiology 💯

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CORE IM @coreimpodcast.bsky.social · 25/06/2025

1/ 🚨 NEW #BeyondJournalClub w/ @nejm.org: REDUCE-AMI What is the long term benefit of beta blockers in patients with preserved EF following an MI? 🖥️: www.coreimpodcast.com/2025/06/25/b...

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CORE IM @coreimpodcast.bsky.social · 23/06/2025

1/ 🚨 NEW #BehindTheScenesInterview: Invasive Fungal Disease Let’s review: 🐞 Antifungal treatments 🐛 Thrush vs. leukoplakia 🐜 Amphotericin in clinical practice 🖥️: www.coreimpodcast.com/2025/06/23/i...

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CORE IM @coreimpodcast.bsky.social · 19/06/2025

1/ 🚨 NEW #12LeadThursday ⤵️ Let’s review a case: Your 50 year old patient has this EKG after a cardiac arrest w/ ROSC. What do you see? 🖥️: www.coreimpodcast.com/2025/06/19/w... 🎥: youtu.be/pxXU9wKTMjI

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CORE IM @coreimpodcast.bsky.social · 17/06/2025

#TriviaTuesday Which is the best test for assessing iron stores? Review the table below ⤵️ 🖥️: www.coreimpodcast.com/2024/03/13/i...

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CORE IM @coreimpodcast.bsky.social · 11/06/2025

7/ Thanks to all for this informative episode! Hosts: @shreyatrivedimd.bsky.social Dr. Samantha Schuetz, Experts: Dr. Audrey Mahajan, Dr. Andrej Spec, Dr. Michael Mansour Peer Review: Dr. Matthew Lee, Dr. Todd McCarty, Kendall Bell PharmD Graphics: Dr. Amy Mu

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CORE IM @coreimpodcast.bsky.social · 11/06/2025

4/ How to test? 🦠 Beta-D-glucan is present in most fungal cell walls but NOT cryptococcus, blastomyces, & mucor - Also a lot of false + 🦠 Galactomannan is present in histoplasma, aspergillus, & fusarium - Low sensitivity

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CORE IM @coreimpodcast.bsky.social · 11/06/2025

3/ Main classes of fungi: 1️⃣ Yeasts - SOME candida - Crypto 2️⃣ Molds - Aspergillus - Mucormycosis 3️⃣ Dimorphics - Mold in the cold ❄️, yeast in the heat 🔥 - Blastomyces - Histoplasma - Coccidioises

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CORE IM @coreimpodcast.bsky.social · 11/06/2025

1/ 🚨 NEW #5Pearls: Invasive Fungal Disease 🦠 Let’s chat about: 1️⃣ What? 2️⃣ Who? 3️⃣ Main classes 4️⃣ Testing 5️⃣ Treatment 🖥️: www.coreimpodcast.com/2025/06/11/i...

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