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Maria Geffen @geffenlab.bsky.social · 13/12/2024

We experience the world through a multitude of senses, and yet most studies of sensory perception focus on one sensory modality at a time. Our paper on how odors affect sound processing in now published in Journal of Neuroscience (1/5). www.jneurosci.org/content/44/4...

A mouse is listening and smelling a cat.

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Maria Geffen @geffenlab.bsky.social · 13/12/2024

We first identified anatomically a direct projection from the piriform cortex to the auditory cortex. (2/5)

Diagram and image of projections from the piriform cortex to the auditory cortex.

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Maria Geffen @geffenlab.bsky.social · 13/12/2024

Next, we recorded neuronal activity in the auditory cortex in awake mice in response to sounds and odors and found that odors upregulate sound responses in some neurons and downregulate sound responses in other neurons. (3/5)

Diagram of the experiment: mouse was presented with odors and sounds. Results: The odor presentation enhanced neuronal responses to sounds in some neurons, suppressed neuronal responses to sounds in other neurons.

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