New preprint alert ‼️ @farkkilab.bsky.social We generated a single-cell spatial atlas of 280 metastatic #ovariancancer and found tumor MHCII as a key driver of tumor ecosystems and clinical outcomes. www.biorxiv.org/content/10.1...
biorxiv.org
Single-cell spatial atlas of high-grade serous ovarian cancer unveils MHC class II as a key driver of spatial tumor ecosystems and clinical outcomes
The tumor microenvironment (TME) is a complex network of interactions between malignant and host cells, yet its orchestration in advanced high-grade serous ovarian carcinoma (HGSC) remains poorly unde...