Marcus Buschbeck and Lab @marcusbuschbeck.bsky.social · 30/10/20256/7 Conclusion: Chromatin composition integrates with metabolic regulation at the NAD⁺ interface. Loss of macroH2A1.1 decouples chromatin–mitochondrial crosstalk, shifting nutrient flux toward glycolysis and instigating secondary organ dysfunction. 210
Marcus Buschbeck and Lab @marcusbuschbeck.bsky.social · 30/10/20257/7 We would like to thank: - Our collaborators from the teams of Emily Bernstein, Manlio Vinciguerra and @poberdoerffer.bsky.social for advice and samples. - Our editor Navdeep Chandel for his guidance. - And most importantly, all members of my lab for support on all levels. 000