Sergi Cuartero @scuartero.bsky.social · 14/04/202510/ Surprisingly, co-IPs revealed that p30 fails to interact with ATF4, while p42 does — impairing downstream signaling. Given ATF4’s key role in the ER stress response, we tested how p30 cells respond to tunicamycin-induced stress 100 0
Sergi Cuartero @scuartero.bsky.social · 14/04/202511/ Indeed, p30-expressing cells were more sensitive to ER stress — revealing a potential vulnerability in CEBPA-mutant AML 100 0
Sergi Cuartero @scuartero.bsky.social · 14/04/202512/ So thankful to everyone who made this possible — Maria for leading the project; the bioinformaticians Gerard Martínez-Cebrián and Lucía Lorenzi; and all our collaborators and funding agencies!🙏🙏🙏 000 0