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Jon Puritz @jonpuritz.marineevoeco.com · 19/11/2024

Becky Taylor@beckystaylor.bsky.social

Wanting to share our new preprint relevant to the #consgen community! Want to measure runs of homozygosity but don’t have enough depth for Plink or BCFtools? We show that it can be done as low as ~3-5X in ROHan but careful parameterization and interpretation is key: www.authorea.com/users/857111...

Accurate runs of homozygosity estimation from low coverage genome sequences in non-model species

Runs of homozygosity (ROH) are increasingly being analyzed using whole genome sequences in non-model species as a measure of inbreeding and to assess demographic history, thus providing useful informa...