Lamming Lab @lamminglab.bsky.social · 18/12/2025Pleased to annouce the publication of our new collaboration with Spencer Haws and @johndenu.bsky.social "Depletion of individual dietary amino acids induce distinct metabolic and chromatin states" 1152
Lamming Lab @lamminglab.bsky.social · 18/12/2025This long-awaited article demonstrates that depletion of individual essential amino acids induces profound changes in the liver epigenome, with AA-specific molecular changes at the level of histone PTMs, the transcriptome, and metabolome www.jbc.org/article/S002...jbc.orgDepletion of individual dietary amino acids induce distinct metabolic and chromatin statesReducing dietary levels of protein or specific essential amino acids (EAAs) promotes favorable metabolic reprogramming, including improved glucose tolerance, increased insulin sensitivity and reduced ... 142