Bind Research @bindresearch.org · 22/09/2026This Sudoku-like puzzle is called assignment, and for gnarly IDPs, it can take weeks to solve. Our recent work combines data from the BMRB with predictions from AlphaFold2 to generate probabilistic assignments for IDPs, streamlining this process. 120
Bind Research @bindresearch.org · 22/09/2026We tested SpinForecast against independently determined assignments for IDPs of increasing size and complexity. Across fully disordered proteins, it assigned approximately 40–75% of signals with 100% confidence, and those assignments were more than 99% accurate. #NMRchat #NMR #ChemSky 120
Bind Research @bindresearch.org · 22/09/2026For the remaining signals, it returned a ranked shortlist of likely candidates, with the correct residue appearing on that shortlist more than 97% of the time. 110
