New paper from our lab! Fabulous and brilliant @carlosalfonsog.bsky.social and @shimengjin.bsky.social, together with fantastic co-authors, show that the neuronal protein ELAV promotes biogenesis of circular RNAs in the brain. This happens through inhibition of forward ("classical") splicing.
👀 New study: The stability of circular RNAs makes them ideal for long-lasting regulatory tasks in neurons. Researchers from the @hilgerslab.bsky.social have now identified the protein ELAV protein as a master regulator of circular RNA production in the nervous system, crucial for brain function.
ie-freiburg.mpg.de
Running circles in my head
Researchers in Freiburg have identified the protein ELAV as a key regulator of circular RNA production in the nervous system, which is crucial for brain function.