Our latest cotranslational folding story is now published @cp-molcell.bsky.social. Really cool (I think) new ideas about how exactly the ribosome directs folding and assembly to make sure complicated proteins mature efficiently in cells.
www.cell.com/molecular-ce...
cell.com
The ribosome synchronizes folding and assembly to promote oligomeric protein biogenesis
Large oligomeric proteins constitute a major fraction of proteomes, but are difficult
to refold in vitro, raising the question of how cells direct their biogenesis. Roeselová
and Shivakumaraswamy et a...
