ME/CFS Science @mecfsscience.org · 04/09/20261) A new paper on ME/CFS is getting media attention: it's about how the chromosomes containing our DNA are folded. These 3D structures can influence the expression of genes. Unfortunately, I don't think this study warrants all the attention... 24016
ME/CFS Science @mecfsscience.org · 04/09/20262) I suspect the media attention is mostly driven by commercial interests, rather than the significance of the scientific findings. The paper comes from the company Oxford BioDynamics (OBD) that developed a new test called EpiSwitch which they applied to ME/CFS. 1100
ME/CFS Science @mecfsscience.org · 04/09/20263) Their previous paper used 200 parameters (based on 3D folding of chromosomes) but they tested it in small samples of less than 100 ME/CFS patients. The controls were not properly matched for age, sex and other factors. That paper already raised some eyebrows... 190
