ME/CFS Science @mecfsscience.org · 28/07/20262) The intervention consisted 10 bi-weekly manual-guided group sessions (50 min each) covering psychoeducation, somatic symptom processing, emotional regulation, and social reintegration. Patients in the control group received treatment as usual. 1110
ME/CFS Science @mecfsscience.org · 28/07/20263) This was a crossover trial so patients in the control group were actually waiting the receive the intervention - a problematic design that could introduce a lot of bias. The study was missing an active control group. 1120
ME/CFS Science @mecfsscience.org · 28/07/20264) Despite this there was no significant effect of the intervention on the outcomes used, namely: somatic symptom burden (SSS-8, primary outcome), and depressive (PHQ-9) and anxiety symptoms (GAD-7). 1130
