ME/CFS Science @mecfsscience.org · 21/07/20262) How does this analysis work? It’s relatively simple: we use DNA results from genetic studies such as DecodeME and match them with RNA databases that give an indication of gene expression in different tissues and cell types. 1142
ME/CFS Science @mecfsscience.org · 21/07/20263) The analysis tests if genes associated with ME/CFS are more commonly used in certain tissues or cell types. You can also use other categories of genes, for example grouped based on biological function. 1142
ME/CFS Science @mecfsscience.org · 21/07/20264) The graph below shows how powerful this technique is. It picks out the relevant cell type in multiple diseases: immune cells in rheumatoid arthritis and asthma, neurons in schizophrenia and epilepsy and pancreatic cells for diabetes. 1143
