ME/CFS Science @mecfsscience.org · 04/07/20263) The study consists of two parts. Stage 1 will form a baseline and is now seeking participants. It will compare calf-muscle metabolism in people with mild ME/CFS to sedentary, healthy controls. 170
ME/CFS Science @mecfsscience.org · 04/07/20264) In Stage 2 (which depends on additional funding) they hope to repeat the as assessments during a mild episode of post-exertional malaise (PEM), triggered by a sub-maximal exercise test. 150
ME/CFS Science @mecfsscience.org · 04/07/20265) The MRI will be done using a 3T scanner. It allows the researchers to measure muscle mitochondrial health, without the need to take invasive muscle biopsies. Participants will be asked to do a brief plantar flexion exercise to tense the calf muscle while in the MRI machine. 170
