ME/CFS Science @mecfsscience.org · 08/06/20265) The authors note that "the samples had been stored for over ten years at -80 °C, which may have altered the fragmentation of certain biomarkers." 170 0
ME/CFS Science @mecfsscience.org · 08/06/20266) The 40 patients and 38 controls were all female but not properly matched (mean age was 51 in patients versus 43 in controls) and there's no info on other potential confounders such as BMI, medication use, etc. 180 0
ME/CFS Science @mecfsscience.org · 08/06/20267) So I have strong doubts about whether these results are reliable. The concentrations were 7 times higher in patients versus controls (126 versus 17 ng/ml), suggesting a technical artefact and differences in sample handling. 190 0