ME/CFS Science @mecfsscience.org · 18/05/20265) Using the MAGMA tool, Paolo could check databases on gene expression to see if the DNA results from ME/CFS patients were enriched in a particular group of genes, tissues, or cell types. 1120
ME/CFS Science @mecfsscience.org · 18/05/20266) The DecodeME preprint did this as well, but it was limited to highlighting a couple of brain regions. With the added MVP samples, Paolo appears to have gotten much stronger results implicating neural synapses in multiple ways. 1130
ME/CFS Science @mecfsscience.org · 18/05/20267) The table below gives the main results for the gene set analysis. The DNA results of ME/CFS patients showed significant results for “Postsynaptic specialization”, “neuron to neuron synapse”, “glutamatergic synapse,”, and many similar categories. 1130
