ME/CFS Science @mecfsscience.org · 18/05/20263) He wanted to add cases from other genetic databases as well, such as the UK Biobank or FinnGen, but that gave the issue that some of the controls overlapped. So for now, DecodeME + MVP was the best he could do, totalling around 19.000 patients. 1140
ME/CFS Science @mecfsscience.org · 18/05/20264) Cases from the Million Veteran Program were based on ICD-codes, so they might contain false positives (patients labeled as ME/CFS who might not have it). But the bump in statistical power was strong enough to get a lot more interesting results. 1130
ME/CFS Science @mecfsscience.org · 18/05/20265) Using the MAGMA tool, Paolo could check databases on gene expression to see if the DNA results from ME/CFS patients were enriched in a particular group of genes, tissues, or cell types. 1120