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ME/CFS Science @mecfsscience.org · 14/02/2026

1) 🧵Been looking at cytokines; small signalling molecules of the immune system. Conclusion: lots of ME/CFS studies on this but inconsistent results. There doesn't seem to be an inflammatory cytokine response (in the blood). Most consistently elevated cytokine was TGF-beta.

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Crazie Daizee @craziedaizee.bsky.social · 14/02/2026

sorry never know which post to reply to all auto-immune response trigger cytokines but the key is severity and activity level? me-cfs seem to severely limit their activity ASAP (new) long-covid people tend to fight to remain active? remember allergies, histamine, exercise trigger cytokines too

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ME/CFS Science @mecfsscience.org · 14/02/2026

2) The table attached is from an outdated review from 2015, but it still includes most of the major cytokines studies in ME/CFS as these were done years ago. Link: sciencedirect.com/science/arti... Interest in cytokine levels seems to have dwindled due to inconsistent results.

sciencedirect.com

Chronic fatigue syndrome and circulating cytokines: A systematic review

There has been much interest in the role of the immune system in the pathophysiology of chronic fatigue syndrome (CFS), as CFS may develop following a…

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