ME/CFS Science @mecfsscience.org · 04/08/20257) Regarding dosage, we found the following info: Fluge et al. 2019 trial 2 infusions (500 mg/m2 of body surface area), 2 weeks apart followed by 4 maintenance infusions Japanese trial 4 times at weekly intervals during the first three weeks (375 mg/m^2/week iv. x 4 times) 150 5
ME/CFS Science @mecfsscience.org · 04/08/20258) There's some more info about the trial in this presentation by Dr. Wakiro Sato from the Berlin conference this year: www.youtube.com/watch?v=n5M1...youtube.comWakiro Sato | International ME/CFS Conference 2025: Rituximab trial in JapanYouTube video by MECFS Research Foundation 150 5
Kira Curious @kikicurious.bsky.social · 04/08/2025Seems a little weird. In a trial of rituximab from the early 2000s (I think, forgive my memory) about half had a response and therefore the overall outcome was non-significant, wouldn't it make more sense to ID the subgroup likely to have a response? 130 3