ME/CFS Science @mecfsscience.org · 11/07/20256) Also interesting: NK cells were quite low in all participants but in those where it was slightly higher, the treatment response was better. The authors speculate that a higher number of baseline NK cells enhanced plasma-cell depletion. 250
ME/CFS Science @mecfsscience.org · 11/07/20257) They are testing a lower dose of Daratumumab in 4 patients with ME/CFS following Sars-Cov-2 who had NK-cells numbers above 125 (x10^6/L). This case series will be published later. 160
ME/CFS Science @mecfsscience.org · 11/07/20258) Caveat: because daratumumab reduces antibodies (IgG reduced IgG by 50%), it could make patients more susceptible to infections. In this small pilot trial, most participants had one or two episodes of a viral upper airway infection but there were no serious adverse reactions. 150
