From Ben Good: competition btwn linked mutations can..enhance selection for modifiers that increase benefits of future mutations, even when they impose a strong direct cost on fitness. However..modest direct benefits can..drive evolutionary dead ends to fixation. www.nature.com/articles/s41...
nature.com
Evolution of evolvability in rapidly adapting populations - Nature Ecology & Evolution
Evolvability modifier mutations alter the rates and benefits of future mutations, but it is difficult to predict when they will be favoured by natural selection. A mathematical framework shows that co...