Dr Chris Morris and I have a new paper in Nucleic Acids Research.
This paper has been a long time in the making & was affected by COVID so we are proud to have it published!
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academic.oup.com/nar/article/...
academic.oup.com
Affinity-selected peptide ligands specifically bind i-motif DNA and modulate c-Myc gene expression
Abstract. c-Myc is an oncogene that is dysregulated in ∼70% of cancers. Its multifaceted function complicates effective drug targeting of the protein. i-Mo