Can small changes in physical activity make a major difference?
On the cover, a meta-analysis suggests that 5 extra minutes of moderate physical activity a day is associated with a reduction of up to 6% of all deaths in the least active adults.
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![Cover of The Lancet's Jan 24, 2026 issue. Quote on cover reads: "Small and realistic increases in [physical activity] of 5 min/day might prevent up to 6% of all deaths."](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:ypu6bwefbbzhcvojdj7mz657/bafkreidwbmr4zhlzsfke3ahcxnhbfefougdjxw23ihgh2hunjeawfibqua)
