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Samay Pande @iamsamayp.bsky.social · 21/02/2025

New paper alert!! Survival of the resistant: When Myxococcus xanthus dies, antibiotic-resistant microbes rise, even without drug exposure. Our manuscript is now online at @currentbiology.bsky.social www.sciencedirect.com/science/arti...

sciencedirect.com

Mass lysis of predatory bacteria drives the enrichment of antibiotic resistance in soil microbial communities

Numerous studies have investigated the effects of antibiotics on the evolution and maintenance of antimicrobial resistance (AMR). However, the impact …

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Samay Pande @iamsamayp.bsky.social · 21/02/2025

We usually blame antibiotics for driving resistance. But what if microbial interactions alone could do the job? We found that the mass death of Myxococcus xanthus releases toxic compounds that enrich antibiotic-resistant bacteria in soil. 🌱🦠

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Samay Pande @iamsamayp.bsky.social · 21/02/2025

We show: •M. xanthus enriches antibiotic-resistant isolates in soil •Starvation-induced lysis of M. xanthus releases growth-inhibitory compounds •Growth inhibitors from M. xanthus lysis enrich resistant bacteria •Death during M. xanthus fruiting body formation impacts soil antibiotic resistomes

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