Excited to share the first published paper from my lab! Postdoc Helen Jordan led this study on 1) how metabolites change differently in inflammation in tissues versus in cells in a dish and 2) the role of one of the most-increased metabolites, soluble sialic acid
www.jbc.org/article/S002...
jbc.org
Metabolomics of in vivo inflammation identifies soluble sialic acid as a conserved myeloid-cell metabolite
During an immune response, metabolism changes dramatically. Metabolites are oxidized
to power immune cell functions, serve as building blocks for proliferation, and act
as effectors to regulate pathog...
