Ben Liffner @benliffner.bsky.social · 12/04/2025Having seen how powerful expansion microscopy was for studying other aspects of parasite biology, we were really keen to see what this technique could allow us to see in mosquito-stage parasites. Being good cell biologists, we first looked at the cool microtubule spindle structures of oocysts! 121 0
Ben Liffner @benliffner.bsky.social · 12/04/2025We could see plenty of other organelles/structures in oocysts too, like the basal complex, apicoplast, apical polar rings, rhoptries, centriolar plaque and more! 100 0
Ben Liffner @benliffner.bsky.social · 12/04/2025Next, we wanted to look at how sporozoites form within the oocyst. But we ran into a problem, oocysts from the same midgut varied massively in their progress through sporozoite development. So how can we compare different oocysts with each other? 110 0