Christophe Zimmer @chzimmer.bsky.social · 10/09/2026Our model assigns an unseen drug to the correct MoA with high accuracy if the MoA was seen before. Most importantly, it can generally flag a drug with a new MoA, a key advantage in the search for drugs against antimicrobial resistant bacteria. 130
Christophe Zimmer @chzimmer.bsky.social · 10/09/2026This is not restricted to E. coli. We obtained similar results on Klebsiella pneumoniae, classified by the WHO as a critical priority pathogen. 110
Christophe Zimmer @chzimmer.bsky.social · 10/09/2026We believe that this approach is a useful complement to traditional growth assays and will speed up the discovery of badly needed antibiotics with novel MoAs. 120
