Akis (Argyris) Papantonis @akispapantonis.bsky.social · 01/07/2026A really cool set of findings.Nitika Taneja @TanejaLab@nitikataneja.bsky.socialVery excited to share our new Nature study! We discovered that replication stress stabilizes CTCF-dependent chromatin loops enclosing stressed nascent DNA, where G9a-mediated heterochromatin protects it from nucleolytic degradation. rdcu.be/frzLg Huge thanks to all our collaborators and co-authors!nature.comReplication-stress-induced chromatin loops protect fork stability - NatureReplication stress induces the formation of transient chromatin loops that enclose de novo heterochromatin-enriched stalled replication forks. 050
