Check out this awesome discovery of the RNA-guided VIPR RNP by the Doudna lab. Everything about the system, from its functional context to its targeting code and structural geometry, is truly remarkable. Congrats to the team!
@kenjmloi.bsky.socialExcited to share our discovery of a new programmable RNA-guided DNA-targeting system hiding inside bacteriophages that predates CRISPR.
We call it VIPR (Viral Interference Programmable Repeat), and it uses an entirely new logic to find its targets.
Thread + link below.
