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Department of Immunobiology at UNIL @dib-unil.bsky.social · 11/12/2024

New paper from @lbernaleau.bsky.social and @rebsamenlab.bsky.social in @jexpmed.bsky.social!

Rebsamen Lab @UNIL@rebsamenlab.bsky.social

Very happy to share our latest work just published in @jexpmed.bsky.social! #Firstpost rupress.org/jem/article/... Our amazing PhD student @lbernaleau.bsky.social shows that CCDC134 controls TLR biogenesis through the ER-chaperone Gp96. #ImmunoSky #innateimmunity #inflammation Quick summary here:

CCDC134 controls TLR biogenesis through the ER chaperone Gp96 | Journal of Experimental Medicine | Rockefeller University Press

A loss-of-function genetic screen identifies the ER-resident protein CCDC134 as an essential regulator of Toll-like receptor (TLR) responses. CCDC134 binds